TY - JOUR
T1 - A model-fitting approach to the estimation of genetic and environmental factors from twin data
AU - Simonoff, Emily A.
AU - Heath, Andrew C.
N1 - Funding Information:
Acknowledgements This research was supported in part by ADAMHA grant AA06781, AA07728, AA07535, MH44828 and DA05588 (A.C.H.) and by a Wellcome Fellowship (E.A.S.). We thank our colleagues Drs Lindon Eaves, John Hewitt, Kenneth S. Kendler, Michael Neale and Andrew Pickles for their support and helpful suggestions.
PY - 1989
Y1 - 1989
N2 - The use of structural equation modelling techniques for twin data are discussed. The technique not only allows estimation of genetic and environmental influences on traits or behaviours, it also gives information on how well such explanations of data fit genetic and environmental models of varying complexity. A model-fitting approach also allows the examination of more complex models than previous types of analysis of twin data provided. Applications to examine causal relationships between traits or behaviours, assortative mating, gene-environment interaction, multivariate analysis and longitudinal studies are briefly discussed. An example illustrating the use of model-fitting applied to twin data to estimate additive genetic, shared environmental and unique environmental factors is given.
AB - The use of structural equation modelling techniques for twin data are discussed. The technique not only allows estimation of genetic and environmental influences on traits or behaviours, it also gives information on how well such explanations of data fit genetic and environmental models of varying complexity. A model-fitting approach also allows the examination of more complex models than previous types of analysis of twin data provided. Applications to examine causal relationships between traits or behaviours, assortative mating, gene-environment interaction, multivariate analysis and longitudinal studies are briefly discussed. An example illustrating the use of model-fitting applied to twin data to estimate additive genetic, shared environmental and unique environmental factors is given.
UR - http://www.scopus.com/inward/record.url?scp=0346562187&partnerID=8YFLogxK
U2 - 10.3109/09540268909089423
DO - 10.3109/09540268909089423
M3 - Article
AN - SCOPUS:0346562187
VL - 1
SP - 297
EP - 305
JO - International Review of Psychiatry
JF - International Review of Psychiatry
SN - 0954-0261
IS - 4
ER -