A missense mutation of the nitric oxide synthase (eNOS) gene (Glu298Asp) in five patients with coronary artery disease

Yuan Lan Liao; Keijiro Saku; Jiafu Ou; Shiro Jimi; Bo Zhang; Kazuyuki Shirai; Kikuo Arakawa

doi:10.1177/000331979905000808

A missense mutation of the nitric oxide synthase (eNOS) gene (Glu²⁹⁸Asp) in five patients with coronary artery disease

Yuan Lan Liao
, Keijiro Saku
, Jiafu Ou
, Shiro Jimi
, Bo Zhang
, Kazuyuki Shirai
, Kikuo Arakawa

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

The authors report five patients with a missense mutation of the endothelial nitric oxide synthase (eNOS) gene (Glu²⁹⁸Asp) who have angiographically proven coronary artery disease (CAD). They compare their clinical findings and coronary arteriographic characteristics. They conclude that these case reports show that this mutation is not solely responsible for development of CAD. Diabetes mellitus, smoking, and hyperlipidemia are other risk factors.

Original language	English
Pages (from-to)	671-676
Number of pages	6
Journal	Angiology
Volume	50
Issue number	8
DOIs	https://doi.org/10.1177/000331979905000808
State	Published - Aug 1999

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abstract = "The authors report five patients with a missense mutation of the endothelial nitric oxide synthase (eNOS) gene (Glu298Asp) who have angiographically proven coronary artery disease (CAD). They compare their clinical findings and coronary arteriographic characteristics. They conclude that these case reports show that this mutation is not solely responsible for development of CAD. Diabetes mellitus, smoking, and hyperlipidemia are other risk factors.",

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AU - Liao, Yuan Lan

AU - Saku, Keijiro

AU - Ou, Jiafu

AU - Jimi, Shiro

AU - Zhang, Bo

AU - Shirai, Kazuyuki

AU - Arakawa, Kikuo

PY - 1999/8

Y1 - 1999/8

N2 - The authors report five patients with a missense mutation of the endothelial nitric oxide synthase (eNOS) gene (Glu298Asp) who have angiographically proven coronary artery disease (CAD). They compare their clinical findings and coronary arteriographic characteristics. They conclude that these case reports show that this mutation is not solely responsible for development of CAD. Diabetes mellitus, smoking, and hyperlipidemia are other risk factors.

AB - The authors report five patients with a missense mutation of the endothelial nitric oxide synthase (eNOS) gene (Glu298Asp) who have angiographically proven coronary artery disease (CAD). They compare their clinical findings and coronary arteriographic characteristics. They conclude that these case reports show that this mutation is not solely responsible for development of CAD. Diabetes mellitus, smoking, and hyperlipidemia are other risk factors.

UR - https://www.scopus.com/pages/publications/0032801596

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DO - 10.1177/000331979905000808

M3 - Article

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SN - 0003-3197

VL - 50

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EP - 676

JO - Angiology

JF - Angiology

IS - 8

ER -

A missense mutation of the nitric oxide synthase (eNOS) gene (Glu²⁹⁸Asp) in five patients with coronary artery disease

Abstract

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