A missense mutation of the nitric oxide synthase (eNOS) gene (Glu298Asp) in five patients with coronary artery disease

Yuan Lan Liao, Keijiro Saku, Jiafu Ou, Shiro Jimi, Bo Zhang, Kazuyuki Shirai, Kikuo Arakawa

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

The authors report five patients with a missense mutation of the endothelial nitric oxide synthase (eNOS) gene (Glu298Asp) who have angiographically proven coronary artery disease (CAD). They compare their clinical findings and coronary arteriographic characteristics. They conclude that these case reports show that this mutation is not solely responsible for development of CAD. Diabetes mellitus, smoking, and hyperlipidemia are other risk factors.

Original languageEnglish
Pages (from-to)671-676
Number of pages6
JournalAngiology
Volume50
Issue number8
DOIs
StatePublished - Aug 1999
Externally publishedYes

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