A microscope for observing intracellular transport with molecular resolution on molecular timescales

Jeremy J. Axelrod; G. Edward Marti; Steven Chu

A microscope for observing intracellular transport with molecular resolution on molecular timescales

Jeremy J. Axelrod
, G. Edward Marti
, Steven Chu

Research output: Contribution to conference › Paper › peer-review

Abstract

We demonstrate an optical microscope that localizes gold nanoparticles to under 1nm in 10µs with illumination conditions compatible with live cell imaging. This enables molecular-scale measurements of molecular motor dynamics in intracellular transport.

Original language	English
State	Published - 2024
Event	2024 Frontiers in Optics, FiO 2024 - Denver, United States Duration: Sep 23 2024 → Sep 26 2024

Conference

Conference	2024 Frontiers in Optics, FiO 2024
Country/Territory	United States
City	Denver
Period	09/23/24 → 09/26/24

Cite this

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title = "A microscope for observing intracellular transport with molecular resolution on molecular timescales",

abstract = "We demonstrate an optical microscope that localizes gold nanoparticles to under 1nm in 10µs with illumination conditions compatible with live cell imaging. This enables molecular-scale measurements of molecular motor dynamics in intracellular transport.",

author = "Axelrod, \{Jeremy J.\} and Marti, \{G. Edward\} and Steven Chu",

note = "Publisher Copyright: {\textcopyright} Optica Publishing Group 2024, {\textcopyright} 2024 The Author(s); 2024 Frontiers in Optics, FiO 2024 ; Conference date: 23-09-2024 Through 26-09-2024",

year = "2024",

language = "English",

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TY - CONF

T1 - A microscope for observing intracellular transport with molecular resolution on molecular timescales

AU - Axelrod, Jeremy J.

AU - Marti, G. Edward

AU - Chu, Steven

PY - 2024

Y1 - 2024

N2 - We demonstrate an optical microscope that localizes gold nanoparticles to under 1nm in 10µs with illumination conditions compatible with live cell imaging. This enables molecular-scale measurements of molecular motor dynamics in intracellular transport.

AB - We demonstrate an optical microscope that localizes gold nanoparticles to under 1nm in 10µs with illumination conditions compatible with live cell imaging. This enables molecular-scale measurements of molecular motor dynamics in intracellular transport.

UR - https://www.scopus.com/pages/publications/85215971562

M3 - Paper

AN - SCOPUS:85215971562

T2 - 2024 Frontiers in Optics, FiO 2024

Y2 - 23 September 2024 through 26 September 2024

ER -

A microscope for observing intracellular transport with molecular resolution on molecular timescales

Abstract

Conference

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