A metabolic synthetic lethal strategy with arginine deprivation and chloroquine leads to cell death in ASS1-deficient sarcomas

Gregory R. Bean, Jeff C. Kremer, Bethany C. Prudner, Aaron D. Schenone, Juo Chin Yao, Matthew B. Schultze, David Y. Chen, Munir R. Tanas, Douglas R. Adkins, John Bomalaski, Brian P. Rubin, Loren S. Michel, Brian A. Van Tine

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Medicine & Life Sciences