13 loci are mapped on chromosome 1 from genetic evidence. The maximum likelihood map presented permits confirmation that Scianna (SC) and a fourteenth locus, phenylketonuria (PKU), are on chromosome 1, although the location of the latter on the PGM1-AMY segment is uncertain. 8 other controversial genetic assignments are rejected, providing a practical demonstration of the resolution which maximum likelihood theory brings to mapping.

Original languageEnglish
Pages (from-to)680-696
Number of pages17
JournalAmerican journal of human genetics
Issue number6
StatePublished - 1979


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