A low-cost photoacoustic microscopy system with a laser diode excitation

Tianheng Wang; Sreyankar Nandy; Hassan S. Salehi; Patrick D. Kumavor; Quing Zhu

doi:10.1364/BOE.5.003053

A low-cost photoacoustic microscopy system with a laser diode excitation

Tianheng Wang
, Sreyankar Nandy
, Hassan S. Salehi
, Patrick D. Kumavor
, Quing Zhu

Department of Biomedical Engineering

Research output: Contribution to journal › Article › peer-review

85 Scopus citations

Abstract

Photoacoustic microscopy (PAM) is capable of mapping microvasculature networks in biological tissue and has demonstrated great potential for biomedical applications. However, the clinical application of the PAM system is limited due to the use of bulky and expensive pulsed laser sources. In this paper, a low-cost optical-resolution PAM system with a pulsed laser diode excitation has been introduced. The lateral resolution of this PAM system was estimated to be 7 μm by imaging a carbon fiber. The phantoms made of polyethylene tubes filled with blood and a mouse ear were imaged to demonstrate the feasibility of this PAM system for imaging biological tissues.

Original language	English
Article number	A3053
Pages (from-to)	3053-3058
Number of pages	6
Journal	Biomedical Optics Express
Volume	5
Issue number	9
DOIs	https://doi.org/10.1364/BOE.5.003053
State	Published - Sep 1 2014

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title = "A low-cost photoacoustic microscopy system with a laser diode excitation",

abstract = "Photoacoustic microscopy (PAM) is capable of mapping microvasculature networks in biological tissue and has demonstrated great potential for biomedical applications. However, the clinical application of the PAM system is limited due to the use of bulky and expensive pulsed laser sources. In this paper, a low-cost optical-resolution PAM system with a pulsed laser diode excitation has been introduced. The lateral resolution of this PAM system was estimated to be 7 μm by imaging a carbon fiber. The phantoms made of polyethylene tubes filled with blood and a mouse ear were imaged to demonstrate the feasibility of this PAM system for imaging biological tissues.",

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AU - Kumavor, Patrick D.

AU - Zhu, Quing

PY - 2014/9/1

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AB - Photoacoustic microscopy (PAM) is capable of mapping microvasculature networks in biological tissue and has demonstrated great potential for biomedical applications. However, the clinical application of the PAM system is limited due to the use of bulky and expensive pulsed laser sources. In this paper, a low-cost optical-resolution PAM system with a pulsed laser diode excitation has been introduced. The lateral resolution of this PAM system was estimated to be 7 μm by imaging a carbon fiber. The phantoms made of polyethylene tubes filled with blood and a mouse ear were imaged to demonstrate the feasibility of this PAM system for imaging biological tissues.

UR - https://www.scopus.com/pages/publications/84928547391

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A low-cost photoacoustic microscopy system with a laser diode excitation

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