A Lab-on-a-chip system integrated with subwavelength periodic patterned metal surfaces for sers-based molecular identification biosensing

  • M. Jin
  • , V. Pully
  • , L. Shui
  • , C. Otto
  • , A. Van Den Berg
  • , E. T. Carlen

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

We present a new lab-on-a-chip (LOC) analysis platform that is integrated with nanotextured surfaces with periodically spaced subwavelength nanogroove and nanopyramid structures with precisely defined pitch λg and separation gaps of ∼2 nm spacing that form high density arrays of hot-spot scattering sites ideally suited for surface enhanced Raman scattering (SERS) and Raman spectroscopy using small sample volumes. The simple fabrication technique requires conventional lithography, wet anisotropic etching and a bonded polymer microfluidic layer. Measured Raman enhancement factors of G∼106 from rhodamine 6G (R6G) on patterned Au surfaces with λg=200 nm are consistent with numerical calculations.

Original languageEnglish
Title of host publication14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010
Pages1250-1252
Number of pages3
StatePublished - 2010
Event14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010 - Groningen, Netherlands
Duration: Oct 3 2010Oct 7 2010

Publication series

Name14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010
Volume2

Conference

Conference14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010
Country/TerritoryNetherlands
CityGroningen
Period10/3/1010/7/10

Keywords

  • Lab-on-a-Chip
  • Nanostructures
  • Plasmonics
  • Surface Enhanced Raman Spectroscopy

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