A hybrid attenuation correction technique to compensate for lung density in 3-d total body PET

Y. C. Tai; K. P. Lin; M. Dahlbom; E. J. Hoffman

doi:10.1109/23.485973

A hybrid attenuation correction technique to compensate for lung density in 3-d total body PET

Y. C. Tai, K. P. Lin, M. Dahlbom, E. J. Hoffman

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16 Scopus citations

Abstract

A hybrid attenuation correction technique (ACT) is under development for 18F-FDG total body positron emission tomography (PET). With a short transmission scan of the thorax, any time within a few days of the imaging session, this technique can correct for attenuation in the entire body. Segmentation, registration, and active contour finding techniques are applied to both emission and short transmission images to locate and map the major attenuating structures in the body. This technique eliminates the need for the patient to remain still from the start of the transmission scan to the end of the emission scan without the added noise of simultaneous or post emission transmission scan measurements. The results of volunteer studies are comparable to standard measured ACT, both visually and quantitatively. The efficient use of scanner time and improved patient comfort make this technique particularly suitable for clinical imaging.

Original language	English
Pages (from-to)	323-330
Number of pages	8
Journal	IEEE Transactions on Nuclear Science
Volume	43
Issue number	1 PART 2
DOIs	https://doi.org/10.1109/23.485973
State	Published - 1996

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title = "A hybrid attenuation correction technique to compensate for lung density in 3-d total body PET",

abstract = "A hybrid attenuation correction technique (ACT) is under development for 18F-FDG total body positron emission tomography (PET). With a short transmission scan of the thorax, any time within a few days of the imaging session, this technique can correct for attenuation in the entire body. Segmentation, registration, and active contour finding techniques are applied to both emission and short transmission images to locate and map the major attenuating structures in the body. This technique eliminates the need for the patient to remain still from the start of the transmission scan to the end of the emission scan without the added noise of simultaneous or post emission transmission scan measurements. The results of volunteer studies are comparable to standard measured ACT, both visually and quantitatively. The efficient use of scanner time and improved patient comfort make this technique particularly suitable for clinical imaging.",

author = "Tai, {Y. C.} and Lin, {K. P.} and M. Dahlbom and Hoffman, {E. J.}",

note = "Funding Information: Manuscript received November 15, 1994; revised November 3, 1995. This work was supported in part by DOE Contract DE-FC03-87-ER 60615, NCI Grant R01-CA56655, and a grant from the Whitaker Foundation. Y.-C. Tai, H. Dahlbom, and E. J. Hoffman are with the Division of Nuclear Medicine and Biophysics, Department of Molecular and Medical Pharmacology, and Department of Radiological Sciences, UCLA School of Medicine, Los Angeles, CA 90024 USA. K.-P. Lin is with the Department of Electrical Engineering, Chung-Yuan University, Taiwan. Publisher Item Identifier S 0018-9499(96)01914-4.",

year = "1996",

doi = "10.1109/23.485973",

language = "English",

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journal = "IEEE Transactions on Nuclear Science",

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AU - Tai, Y. C.

AU - Lin, K. P.

AU - Dahlbom, M.

AU - Hoffman, E. J.

N1 - Funding Information: Manuscript received November 15, 1994; revised November 3, 1995. This work was supported in part by DOE Contract DE-FC03-87-ER 60615, NCI Grant R01-CA56655, and a grant from the Whitaker Foundation. Y.-C. Tai, H. Dahlbom, and E. J. Hoffman are with the Division of Nuclear Medicine and Biophysics, Department of Molecular and Medical Pharmacology, and Department of Radiological Sciences, UCLA School of Medicine, Los Angeles, CA 90024 USA. K.-P. Lin is with the Department of Electrical Engineering, Chung-Yuan University, Taiwan. Publisher Item Identifier S 0018-9499(96)01914-4.

PY - 1996

Y1 - 1996

N2 - A hybrid attenuation correction technique (ACT) is under development for 18F-FDG total body positron emission tomography (PET). With a short transmission scan of the thorax, any time within a few days of the imaging session, this technique can correct for attenuation in the entire body. Segmentation, registration, and active contour finding techniques are applied to both emission and short transmission images to locate and map the major attenuating structures in the body. This technique eliminates the need for the patient to remain still from the start of the transmission scan to the end of the emission scan without the added noise of simultaneous or post emission transmission scan measurements. The results of volunteer studies are comparable to standard measured ACT, both visually and quantitatively. The efficient use of scanner time and improved patient comfort make this technique particularly suitable for clinical imaging.

AB - A hybrid attenuation correction technique (ACT) is under development for 18F-FDG total body positron emission tomography (PET). With a short transmission scan of the thorax, any time within a few days of the imaging session, this technique can correct for attenuation in the entire body. Segmentation, registration, and active contour finding techniques are applied to both emission and short transmission images to locate and map the major attenuating structures in the body. This technique eliminates the need for the patient to remain still from the start of the transmission scan to the end of the emission scan without the added noise of simultaneous or post emission transmission scan measurements. The results of volunteer studies are comparable to standard measured ACT, both visually and quantitatively. The efficient use of scanner time and improved patient comfort make this technique particularly suitable for clinical imaging.

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A hybrid attenuation correction technique to compensate for lung density in 3-d total body PET

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