TY - JOUR
T1 - A high molecular weight species of soluble elastin
AU - Foster, Judith Ann
AU - Mecham, Robert P.
AU - Franzblau, Carl
N1 - Funding Information:
~The authors acknowledge financial support of the National Institutes of Health Grants HL-15964 and NOI H-R-42934.
PY - 1976/10/18
Y1 - 1976/10/18
N2 - The isolation of a high molecular weight species (130-140,000 daltons) of soluble elastin from the aortas of lathyritic chicks is described. In comparison to chick tropoelastin, the higher molecular weight material possesses an increased amount of acidic and hydroxyl amino acids and in contrast to tropoelastin, contains histidine, methionine and cystine residues. This molecular weight species of soluble elastin is susceptible to proteolytic degradation and can be shown to readily breakdown to lower molecular weight components including tropoelastin.
AB - The isolation of a high molecular weight species (130-140,000 daltons) of soluble elastin from the aortas of lathyritic chicks is described. In comparison to chick tropoelastin, the higher molecular weight material possesses an increased amount of acidic and hydroxyl amino acids and in contrast to tropoelastin, contains histidine, methionine and cystine residues. This molecular weight species of soluble elastin is susceptible to proteolytic degradation and can be shown to readily breakdown to lower molecular weight components including tropoelastin.
UR - https://www.scopus.com/pages/publications/0017152654
U2 - 10.1016/S0006-291X(76)80169-6
DO - 10.1016/S0006-291X(76)80169-6
M3 - Article
C2 - 826247
AN - SCOPUS:0017152654
SN - 0006-291X
VL - 72
SP - 1399
EP - 1406
JO - Biochemical and Biophysical Research Communications
JF - Biochemical and Biophysical Research Communications
IS - 4
ER -