A good turn for DNA: The structure of integration host factor bound to DNA

Tom Ellenberger, Arthur Landy

Research output: Contribution to journalReview articlepeer-review

34 Scopus citations

Abstract

The crystal structure of integration host factor (IHF) complexed with DNA shows how a small heterodimeric protein can induce a big bend in DNA. IHF exerts leverage in the minor groove and wraps DNA around the body of the protein, providing another example of sequence-specific recognition of the minor groove.

Original languageEnglish
Pages (from-to)153-157
Number of pages5
JournalStructure
Volume5
Issue number2
DOIs
StatePublished - 1997

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