Abstract
Path analysis gives evidence of genetic heritability (.425) for serum IgE levels. Complex segregation analysis indicates, in addition to significant polygenic heritability, a major regulatory locus RE, with homozygotes re/re maintaining persistently high levels of IgE. The gene frequency of re is .489, and the displacement is 1.67 standard deviations.
| Original language | English |
|---|---|
| Pages (from-to) | 46-58 |
| Number of pages | 13 |
| Journal | American journal of human genetics |
| Volume | 30 |
| Issue number | 1 |
| State | Published - 1978 |