A General and Stereocontrolled Total Synthesis of Leukotriene B4 and Analogues

K. C. Nicolaou; R. E. Zipkin; R. E. Dolle; B. D. Harris

doi:10.1021/ja00324a024

A General and Stereocontrolled Total Synthesis of Leukotriene B₄ and Analogues

K. C. Nicolaou, R. E. Zipkin, R. E. Dolle, B. D. Harris

Center for Drug Discovery

Research output: Contribution to journal › Article › peer-review

108 Scopus citations

Abstract

A new, general, and stereocontrolled total synthesis of leukotriene B₄ (1) is disclosed. The application of the methodology to the synthesis of several novel analogues of leukotriene B₄ is also described.

Original language	English
Pages (from-to)	3548-3551
Number of pages	4
Journal	Journal of the American Chemical Society
Volume	106
Issue number	12
DOIs	https://doi.org/10.1021/ja00324a024
State	Published - Jan 1984

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title = "A General and Stereocontrolled Total Synthesis of Leukotriene B4 and Analogues",

abstract = "A new, general, and stereocontrolled total synthesis of leukotriene B4 (1) is disclosed. The application of the methodology to the synthesis of several novel analogues of leukotriene B4 is also described.",

author = "Nicolaou, {K. C.} and Zipkin, {R. E.} and Dolle, {R. E.} and Harris, {B. D.}",

year = "1984",

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AU - Harris, B. D.

PY - 1984/1

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N2 - A new, general, and stereocontrolled total synthesis of leukotriene B4 (1) is disclosed. The application of the methodology to the synthesis of several novel analogues of leukotriene B4 is also described.

AB - A new, general, and stereocontrolled total synthesis of leukotriene B4 (1) is disclosed. The application of the methodology to the synthesis of several novel analogues of leukotriene B4 is also described.

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A General and Stereocontrolled Total Synthesis of Leukotriene B₄ and Analogues

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