A fully corrected fan beam OSEM algorithm for dirty emitters

Norbert N. Agbeko, Joseph A. O'Sullivan, Richard Laforest, Ju Chieh Cheng

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Non-standard radionuclides used in PET imaging introduce additional factors into the imaging model that need to be properly accounted for in order to ensure quantitative accuracy. One of these factors is the emission of cascade gamma rays whereby additional photons of different energies are emitted concurrently with the two anti-parallel 511 keV gamma rays. The emission of these cascade gamma rays has no angular correlation to the emission of the two 511 keV photons. Thus the cascade gamma rays produce a background effect similar to that of random coincidences but with different statistics. We present a method for estimating the shape of the cascade distribution using an estimate of the activity distribution and attenuation map in a manner similar to the estimation of single scatter. The estimated cascade distribution and an estimate for the single scatter distribution are incorporated into a new OSEM algorithm to reconstruct an image that is corrected for cascade and scatter. The resulting image has the background effect removed and has better contrast than when reconstructed using the standard OSEM algorithm.

Original languageEnglish
Title of host publication2009 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2009
Pages3269-3272
Number of pages4
DOIs
StatePublished - Dec 1 2009
Event2009 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2009 - Orlando, FL, United States
Duration: Oct 25 2009Oct 31 2009

Publication series

NameIEEE Nuclear Science Symposium Conference Record
ISSN (Print)1095-7863

Conference

Conference2009 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2009
CountryUnited States
CityOrlando, FL
Period10/25/0910/31/09

Fingerprint Dive into the research topics of 'A fully corrected fan beam OSEM algorithm for dirty emitters'. Together they form a unique fingerprint.

  • Cite this

    Agbeko, N. N., O'Sullivan, J. A., Laforest, R., & Cheng, J. C. (2009). A fully corrected fan beam OSEM algorithm for dirty emitters. In 2009 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2009 (pp. 3269-3272). [5401725] (IEEE Nuclear Science Symposium Conference Record). https://doi.org/10.1109/NSSMIC.2009.5401725