@article{c3a175ea294342609bf6af2957f2113d,
title = "A framework for detecting noncoding rare-variant associations of large-scale whole-genome sequencing studies",
abstract = "STAARpipeline is a comprehensive framework for flexible and scalable rare-variant association analysis using whole-genome sequencing data and annotation information.",
author = "{NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium} and {TOPMed Lipids Working Group} and Zilin Li and Xihao Li and Hufeng Zhou and Gaynor, {Sheila M.} and Selvaraj, {Margaret Sunitha} and Theodore Arapoglou and Corbin Quick and Yaowu Liu and Han Chen and Ryan Sun and Rounak Dey and Arnett, {Donna K.} and Auer, {Paul L.} and Bielak, {Lawrence F.} and Bis, {Joshua C.} and Blackwell, {Thomas W.} and John Blangero and Eric Boerwinkle and Bowden, {Donald W.} and Brody, {Jennifer A.} and Cade, {Brian E.} and Conomos, {Matthew P.} and Adolfo Correa and Cupples, {L. Adrienne} and Curran, {Joanne E.} and {de Vries}, {Paul S.} and Ravindranath Duggirala and Nora Franceschini and Freedman, {Barry I.} and G{\"o}ring, {Harald H.H.} and Xiuqing Guo and Kalyani, {Rita R.} and Charles Kooperberg and Kral, {Brian G.} and Lange, {Leslie A.} and Lin, {Bridget M.} and Ani Manichaikul and Manning, {Alisa K.} and Martin, {Lisa W.} and Mathias, {Rasika A.} and Meigs, {James B.} and Mitchell, {Braxton D.} and Montasser, {May E.} and Morrison, {Alanna C.} and Take Naseri and O{\textquoteright}Connell, {Jeffrey R.} and Palmer, {Nicholette D.} and Peyser, {Patricia A.} and Psaty, {Bruce M.} and Raffield, {Laura M.} and Susan Redline and Reiner, {Alexander P.} and Reupena, {Muagututi{\textquoteright}a Sefuiva} and Rice, {Kenneth M.} and Rich, {Stephen S.} and Smith, {Jennifer A.} and Taylor, {Kent D.} and Taub, {Margaret A.} and Vasan, {Ramachandran S.} and Weeks, {Daniel E.} and Wilson, {James G.} and Yanek, {Lisa R.} and Wei Zhao and Namiko Abe and Gon{\c c}alo Abecasis and Francois Aguet and Christine Albert and Laura Almasy and Alvaro Alonso and Seth Ament and Peter Anderson and Pramod Anugu and Deborah Applebaum-Bowden and Kristin Ardlie and Dan Arking and Allison Ashley-Koch and Stella Aslibekyan and Tim Assimes and Dimitrios Avramopoulos and Najib Ayas and Adithya Balasubramanian and John Barnard and Kathleen Barnes and Barr, {R. Graham} and Emily Barron-Casella and Lucas Barwick and Terri Beaty and Gerald Beck and Diane Becker and Lewis Becker and Rebecca Beer and Amber Beitelshees and Emelia Benjamin and Takis Benos and Marcos Bezerra and Nathan Blue and Russell Bowler and Ulrich Broeckel and Jai Broome and Deborah Brown and Karen Bunting and Esteban Burchard and Carlos Bustamante and Erin Buth and Jonathan Cardwell and Vincent Carey and Julie Carrier and April Carson and Cara Carty and Richard Casaburi and {Casas Romero}, {Juan P.} and James Casella and Peter Castaldi and Mark Chaffin and Christy Chang and Chang, {Yi Cheng} and Daniel Chasman and Sameer Chavan and Chen, {Bo Juen} and Chen, {Wei Min} and Chen, {Yii Der Ida} and Michael Cho and Choi, {Seung Hoan} and Chuang, {Lee Ming} and Mina Chung and Chung, {Ren Hua} and Clary Clish and Suzy Comhair and Elaine Cornell and Carolyn Crandall and James Crapo and Jeffrey Curtis and Brian Custer and Coleen Damcott and Dawood Darbar and Sean David and Colleen Davis and Michelle Daya and {de Andrade}, Mariza and Fuentes, {Lisa de las} and Michael DeBaun and Ranjan Deka and Dawn DeMeo and Scott Devine and Huyen Dinh and Harsha Doddapaneni and Qing Duan and Shannon Dugan-Perez and Durda, {Jon Peter} and Dutcher, {Susan K.} and Charles Eaton and Lynette Ekunwe and {El Boueiz}, Adel and Patrick Ellinor and Leslie Emery and Serpil Erzurum and Charles Farber and Jesse Farek and Tasha Fingerlin and Matthew Flickinger and Myriam Fornage and Chris Frazar and Mao Fu and Fullerton, {Stephanie M.} and Lucinda Fulton and Stacey Gabriel and Weiniu Gan and Shanshan Gao and Yan Gao and Margery Gass and Heather Geiger and Bruce Gelb and Mark Geraci and Soren Germer and Robert Gerszten and Auyon Ghosh and Richard Gibbs and Chris Gignoux and Mark Gladwin and David Glahn and Stephanie Gogarten and Gong, {Da Wei} and Sharon Graw and Gray, {Kathryn J.} and Daniel Grine and Colin Gross and Gu, {C. Charles} and Yue Guan and Namrata Gupta and Michael Hall and Yi Han and Patrick Hanly and Daniel Harris and Hawley, {Nicola L.} and Jiang He and Ben Heavner and Susan Heckbert and Ryan Hernandez and Rao, {D. C.} and Sung, {Yun Ju}",
note = "Publisher Copyright: {\textcopyright} The Author(s), under exclusive licence to Springer Nature America, Inc. 2022. Springer Nature or its licensor holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law..",
year = "2022",
month = dec,
doi = "10.1038/s41592-022-01640-x",
language = "English",
volume = "19",
pages = "1599--1611",
journal = "Nature Methods",
issn = "1548-7091",
number = "12",
}