A frailty approach for modelling diseases with variable age of onset in families: The NHBLI Family Heart Study

Keyphrases

• Age of Onset 100%
• Coronary Artery Disease 33%
• Covariate Interaction 33%
• Disease Data 33%
• Disease Status 33%
• Dominant Gene 33%
• Environmental Risk Factors 33%
• Familial Environment 33%
• Familial Risk 33%
• Fraility 33%
• Frailty 100%
• Frailty Model 33%
• Gamma Distribution 33%
• Gene Action 33%
• Genetic Risk 33%
• Genotype 33%
• Hazard Function 33%
• Heart Blood 33%
• Heart-lung 33%
• Interaction Effect 33%
• Joint Estimation 33%
• Latent Risk 33%
• Law 33%
• Major Gene 33%
• Mendelian Transmission 33%
• Modelling Diseases 100%
• National Heart 33%
• Nuclear Family 33%
• Polygene 66%
• Recessive Genes 33%
• Relative Risk 33%
• Residual Correlation 33%
• Risk Factors 33%
• Shared Environment 66%
• Simulation Study 33%
• Two-point Distribution 66%

Biochemistry, Genetics and Molecular Biology

• Disease Modeling 100%
• Dominant Gene 33%
• Gene Activity 33%
• Genetics 100%
• Genotyping 33%
• Major Gene 33%
• Polygene 66%
• Recessive Gene 33%

Mathematics

• Covariate 66%
• Disease Status 33%
• Hazard Function 33%
• Interaction Effect 33%
• Relative Risk 33%
• Residuals 100%
• Simulation Study 33%