Abstract

The finite deformation, anisotropic, biphasic finite element model of cell matrix interactions in the intervertebral disc was discussed. The model was used as a reference for validation of the nonlinear FEM predictions at equilibrium. The results suggested that zonal differences in cell micromechanical environment play a role in known differences in the biosynthetic response of the disc cells.

Original languageEnglish
Pages (from-to)799-800
Number of pages2
JournalAmerican Society of Mechanical Engineers, Bioengineering Division (Publication) BED
Volume50
StatePublished - 2001
EventProceedings of the 2001 Bioengineering Conference - Snowbird, UT, United States
Duration: Jun 27 2001Jul 1 2001

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