A fast 512-element ring array photoacoustic imaging system for small animals

John Gamelin; Anastasios Maurudis; Andres Aguirre; Fei Huang; Puyun Guo; Lihong V. Wang; Quing Zhu

doi:10.1117/12.812406

A fast 512-element ring array photoacoustic imaging system for small animals

John Gamelin
, Anastasios Maurudis
, Andres Aguirre
, Fei Huang
, Puyun Guo
, Lihong V. Wang
, Quing Zhu

Department of Biomedical Engineering

Research output: Contribution to journal › Conference article › peer-review

6 Scopus citations

Abstract

A 512-element photoacoustic tomography system for small animal imaging using a ring ultrasound array has been developed. The system features a 5 MHz piezocomposite transducer array formed into a complete circular aperture. Custom receiver electronics consisting of dedicated preamplifiers, 8:1 multiplexed post-amplifiers, and a 64-channel data acquisition module provide full tomographic imaging at up to 8 frames/second. We present details of the system design along with characterization results of the resolution, imaging volume, and sensitivity. Small animal imaging performance is demonstrated through images of mice brain vasculature at different depths and real-time spectroscopic scans. This system enables real-time tomographic imaging for functional photoacoustic studies for the first time.

Original language	English
Article number	71770B
Journal	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume	7177
DOIs	https://doi.org/10.1117/12.812406
State	Published - 2009
Event	Photons Plus Ultrasound: Imaging and Sensing 2009 - San Jose, CA, United States Duration: Jan 25 2009 → Jan 28 2009

Keywords

Backprojection
Photoacoustic tomography
Real-time imaging
Reconstruction

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10.1117/12.812406

Cite this

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title = "A fast 512-element ring array photoacoustic imaging system for small animals",

abstract = "A 512-element photoacoustic tomography system for small animal imaging using a ring ultrasound array has been developed. The system features a 5 MHz piezocomposite transducer array formed into a complete circular aperture. Custom receiver electronics consisting of dedicated preamplifiers, 8:1 multiplexed post-amplifiers, and a 64-channel data acquisition module provide full tomographic imaging at up to 8 frames/second. We present details of the system design along with characterization results of the resolution, imaging volume, and sensitivity. Small animal imaging performance is demonstrated through images of mice brain vasculature at different depths and real-time spectroscopic scans. This system enables real-time tomographic imaging for functional photoacoustic studies for the first time.",

keywords = "Backprojection, Photoacoustic tomography, Real-time imaging, Reconstruction",

author = "John Gamelin and Anastasios Maurudis and Andres Aguirre and Fei Huang and Puyun Guo and Wang, \{Lihong V.\} and Quing Zhu",

year = "2009",

doi = "10.1117/12.812406",

language = "English",

volume = "7177",

journal = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",

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note = "Photons Plus Ultrasound: Imaging and Sensing 2009 ; Conference date: 25-01-2009 Through 28-01-2009",

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TY - JOUR

T1 - A fast 512-element ring array photoacoustic imaging system for small animals

AU - Gamelin, John

AU - Maurudis, Anastasios

AU - Aguirre, Andres

AU - Huang, Fei

AU - Guo, Puyun

AU - Wang, Lihong V.

AU - Zhu, Quing

PY - 2009

Y1 - 2009

N2 - A 512-element photoacoustic tomography system for small animal imaging using a ring ultrasound array has been developed. The system features a 5 MHz piezocomposite transducer array formed into a complete circular aperture. Custom receiver electronics consisting of dedicated preamplifiers, 8:1 multiplexed post-amplifiers, and a 64-channel data acquisition module provide full tomographic imaging at up to 8 frames/second. We present details of the system design along with characterization results of the resolution, imaging volume, and sensitivity. Small animal imaging performance is demonstrated through images of mice brain vasculature at different depths and real-time spectroscopic scans. This system enables real-time tomographic imaging for functional photoacoustic studies for the first time.

AB - A 512-element photoacoustic tomography system for small animal imaging using a ring ultrasound array has been developed. The system features a 5 MHz piezocomposite transducer array formed into a complete circular aperture. Custom receiver electronics consisting of dedicated preamplifiers, 8:1 multiplexed post-amplifiers, and a 64-channel data acquisition module provide full tomographic imaging at up to 8 frames/second. We present details of the system design along with characterization results of the resolution, imaging volume, and sensitivity. Small animal imaging performance is demonstrated through images of mice brain vasculature at different depths and real-time spectroscopic scans. This system enables real-time tomographic imaging for functional photoacoustic studies for the first time.

KW - Backprojection

KW - Photoacoustic tomography

KW - Real-time imaging

KW - Reconstruction

UR - https://www.scopus.com/pages/publications/66249140960

U2 - 10.1117/12.812406

DO - 10.1117/12.812406

M3 - Conference article

AN - SCOPUS:66249140960

SN - 1605-7422

VL - 7177

JO - Progress in Biomedical Optics and Imaging - Proceedings of SPIE

JF - Progress in Biomedical Optics and Imaging - Proceedings of SPIE

M1 - 71770B

T2 - Photons Plus Ultrasound: Imaging and Sensing 2009

Y2 - 25 January 2009 through 28 January 2009

ER -

A fast 512-element ring array photoacoustic imaging system for small animals

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Keywords

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