A farnesyltransferase inhibitor activates lysosomes and reduces tau pathology in mice with tauopathy

Israel Hernandez, Gabriel Luna, Jennifer N. Rauch, Surya A. Reis, Michel Giroux, Celeste M. Karch, Daniel Boctor, Youssef E. Sibih, Nadia J. Storm, Antonio Diaz, Susmita Kaushik, Cezary Zekanowski, Alexander A. Kang, Cassidy R. Hinman, Vesna Cerovac, Elmer Guzman, Honjun Zhou, Stephen J. Haggarty, Alison M. Goate, Steven K. FisherAna M. Cuervo, Kenneth S. Kosik

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Keyphrases

Pharmacology, Toxicology and Pharmaceutical Science

Neuroscience

Biochemistry, Genetics and Molecular Biology