A diversity of GABA receptors in the retina

Peter D. Lukasiewicz; Colleen R. Shields

doi:10.1006/scdb.1998.0238

A diversity of GABA receptors in the retina

Peter D. Lukasiewicz, Colleen R. Shields

Research output: Contribution to journal › Article › peer-review

57 Scopus citations

Abstract

GABA, a major inhibitory transmitter in the vertebrate retina, plays important roles in processing visual information. There are three functional families of retinal GABA receptors, the ionotropic GABA_A and GABA_C receptors and the metabotropic GABA_B receptor. GABA_C receptors are enriched in the retina, compared to other parts of the CNS. GABA_C and GABA_B receptors are found on subsets of neurons, whereas GABA_A receptors are ubiquitous. The distinct functional properties of GABA_A, GABA_B and GABA_C receptors suggests that individual neurons with different receptor complements have unique responses to GABA.

Original language	English
Pages (from-to)	293-299
Number of pages	7
Journal	Seminars in Cell and Developmental Biology
Volume	9
Issue number	3
DOIs	https://doi.org/10.1006/scdb.1998.0238
State	Published - Jun 1998

Keywords

GABA receptor
GABA receptor
GABA receptor
Retina
Visual processing

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10.1006/scdb.1998.0238

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abstract = "GABA, a major inhibitory transmitter in the vertebrate retina, plays important roles in processing visual information. There are three functional families of retinal GABA receptors, the ionotropic GABAA and GABAC receptors and the metabotropic GABAB receptor. GABAC receptors are enriched in the retina, compared to other parts of the CNS. GABAC and GABAB receptors are found on subsets of neurons, whereas GABAA receptors are ubiquitous. The distinct functional properties of GABAA, GABAB and GABAC receptors suggests that individual neurons with different receptor complements have unique responses to GABA.",

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A diversity of GABA receptors in the retina

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