A conformational switch regulates receptor-G protein interaction

N. Gautam

doi:10.1016/S0969-2126(03)00054-6

A conformational switch regulates receptor-G protein interaction

N. Gautam

Research output: Contribution to journal › Short survey › peer-review

12 Scopus citations

Abstract

A peptide specific to a G protein γ subunit C terminus undergoes a conformational shift concordant with receptor activation, providing direct support for a long-standing proposal that a conformational switch in the γ subunit tail mediates G protein activation by a receptor.

Original language	English
Pages (from-to)	359-360
Number of pages	2
Journal	Structure
Volume	11
Issue number	4
DOIs	https://doi.org/10.1016/S0969-2126(03)00054-6
State	Published - Apr 1 2003

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title = "A conformational switch regulates receptor-G protein interaction",

abstract = "A peptide specific to a G protein γ subunit C terminus undergoes a conformational shift concordant with receptor activation, providing direct support for a long-standing proposal that a conformational switch in the γ subunit tail mediates G protein activation by a receptor.",

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AB - A peptide specific to a G protein γ subunit C terminus undergoes a conformational shift concordant with receptor activation, providing direct support for a long-standing proposal that a conformational switch in the γ subunit tail mediates G protein activation by a receptor.

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A conformational switch regulates receptor-G protein interaction

Abstract

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