A conformational switch regulates receptor-G protein interaction

Research output: Contribution to journalShort surveypeer-review

12 Scopus citations

Abstract

A peptide specific to a G protein γ subunit C terminus undergoes a conformational shift concordant with receptor activation, providing direct support for a long-standing proposal that a conformational switch in the γ subunit tail mediates G protein activation by a receptor.

Original languageEnglish
Pages (from-to)359-360
Number of pages2
JournalStructure
Volume11
Issue number4
DOIs
StatePublished - Apr 1 2003

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