A computer simulation of evolutionary forces controlling the size of a multigene family

J. M. Hood, H. V. Huang, L. Hood

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

A Monte Carlo-type simulation of the evolution of a multigene family was performed. The model was designed to study the selective forces which may control the size of a multigene family. As expected, we find that direct selection on the size of the multigene family can control its size. More important, we find that selection acting upon the family as a single functional unit, in conjunction with homologous but unequal crossing over, can also control the size of a multigene family.

Original languageEnglish
Pages (from-to)181-196
Number of pages16
JournalJournal of Molecular Evolution
Volume15
Issue number3
DOIs
StatePublished - Sep 1 1980

Keywords

  • Homologous but unequal crossing over
  • Monte Carlo simulation
  • Multigene Family, size
  • Selective forces

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