A Comprehensive Resource for Induced Pluripotent Stem Cells from Patients with Primary Tauopathies

Tau Consortium Stem Cell Group

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

In this article, Karch, Temple and colleagues describe a resource of fibroblasts, patient-derived induced pluripotent stem cells, and genome engineered stem cells with comprehensive clinical histories that can be accessed by the scientific community for disease modeling and development of novel therapeutics for primary tauopathies.

Original languageEnglish
Pages (from-to)939-955
Number of pages17
JournalStem Cell Reports
Volume13
Issue number5
DOIs
StatePublished - Nov 12 2019

Keywords

  • CRISPR/Cas9
  • MAPT
  • corticobasal degeneration
  • fibroblasts
  • frontotemporal dementia
  • induced pluripotent stem cells
  • neural progenitor cells
  • progressive supranuclear palsy
  • tau
  • tauopathy

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