A compact NIR fluorescence imaging system with goggle display for intraoperative guidance

Shengkui Gao, Suman Mondal, Nan Zhu, Rongguang Liang, Samuel Achilefu, Viktor Gruev

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Abstract

Near infra-red (NIR) fluorescence imaging offers high sensitivity and specificity for cancer detection and tumor margin localization. In this paper, a compact and wearable NIR fluorescence imaging system (FIS) for image guided surgery is presented. The proposed FIS captures 27 frames per second of both NIR and visible spectrum data, allowing for minimum detection of 10nM of ICG concentration. The design tradeoffs of the complete system are carefully analyzed. The performance of the proposed FIS is evaluated under both sensitivity test and experimental mouse study. The imaging system is currently used in clinical trials for imaging sentinel lymph nodes in breast cancer and melanoma patients.

Original languageEnglish
Title of host publication2015 IEEE International Symposium on Circuits and Systems, ISCAS 2015
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages1622-1625
Number of pages4
ISBN (Electronic)9781479983919
DOIs
StatePublished - Jul 27 2015
EventIEEE International Symposium on Circuits and Systems, ISCAS 2015 - Lisbon, Portugal
Duration: May 24 2015May 27 2015

Publication series

NameProceedings - IEEE International Symposium on Circuits and Systems
Volume2015-July
ISSN (Print)0271-4310

Conference

ConferenceIEEE International Symposium on Circuits and Systems, ISCAS 2015
CountryPortugal
CityLisbon
Period05/24/1505/27/15

Keywords

  • CMOS imaging sensor
  • NIR fluorescence imaging
  • image guided surgery
  • sensor system
  • wearable device

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    Gao, S., Mondal, S., Zhu, N., Liang, R., Achilefu, S., & Gruev, V. (2015). A compact NIR fluorescence imaging system with goggle display for intraoperative guidance. In 2015 IEEE International Symposium on Circuits and Systems, ISCAS 2015 (pp. 1622-1625). [7168960] (Proceedings - IEEE International Symposium on Circuits and Systems; Vol. 2015-July). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/ISCAS.2015.7168960