A collection of 1814 human chromosome 7-specific STSs

Gerard G. Bouffard, Leslie M. Iyer, Jacquelyn R. Idol, Valerie V. Braden, Aimee F. Cunningham, Lauren A. Weintraub, Rose M. Mohr-Tidwell, Dale C. Peluso, Robert S. Fulton, Mary P. Leckie, Eric D. Green

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

An established goal of the ongoing Human Genome Project is the development and mapping of sequence-tagged sites (STSs) every 100 kb, on average, across all human chromosomes. En route to constructing such a physical map of human chromosome 7, we have generated 1814 chromosome 7-specific STSs. The corresponding PCR assays were designed by the use of DNA sequence determined in our laboratory (79%) or generated elsewhere (21%) and were demonstrated to be suitable for screening yeast artificial chromosome (YAC) libraries. This collection provides the requisite landmarks for constructing a physical map of chromosome 7 at < 100-kb average spacing of STSs.

Original languageEnglish
Pages (from-to)59-64
Number of pages6
JournalGenome research
Volume7
Issue number1
DOIs
StatePublished - Jan 1997

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