A chemosensitive pediatric extraosseous osteosarcoma: Case report and review of the literature

Karen Wodowski; D. Ashley Hill; Alberto S. Pappo; Stephen J. Shochat; Larry E. Kun; Sheri L. Spunt

doi:10.1097/00043426-200301000-00015

A chemosensitive pediatric extraosseous osteosarcoma: Case report and review of the literature

Karen Wodowski, D. Ashley Hill, Alberto S. Pappo, Stephen J. Shochat, Larry E. Kun, Sheri L. Spunt

Division of Anatomic and Molecular Pathology (AMP)

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

Osteosarcoma arising in soft tissues is exceedingly rare in children. The tumor most often affects older adults, involves the lower extremity, responds poorly to chemotherapy, and carries a grave prognosis. The authors describe a 12-year-old girl with an extraosseous osteosarcoma of the left sternocleidomastoid muscle with pulmonary metastases. The patient responded well to neoadjuvant chemotherapy and remains disease-free nearly 3 years after her initial diagnosis. The authors review available information about this disease in children and adults. Children with extraosseous osteosarcoma may have a more favorable response to treatment than adults; thus, a curative approach using combined modality therapy appears warranted.

Original language	English
Pages (from-to)	73-77
Number of pages	5
Journal	Journal of Pediatric Hematology/Oncology
Volume	25
Issue number	1
DOIs	https://doi.org/10.1097/00043426-200301000-00015
State	Published - Jan 2003

Keywords

Child
Extraosseous
Extraskeletal
Neck
Osteosarcoma
Soft tissue neoplasm

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abstract = "Osteosarcoma arising in soft tissues is exceedingly rare in children. The tumor most often affects older adults, involves the lower extremity, responds poorly to chemotherapy, and carries a grave prognosis. The authors describe a 12-year-old girl with an extraosseous osteosarcoma of the left sternocleidomastoid muscle with pulmonary metastases. The patient responded well to neoadjuvant chemotherapy and remains disease-free nearly 3 years after her initial diagnosis. The authors review available information about this disease in children and adults. Children with extraosseous osteosarcoma may have a more favorable response to treatment than adults; thus, a curative approach using combined modality therapy appears warranted.",

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AB - Osteosarcoma arising in soft tissues is exceedingly rare in children. The tumor most often affects older adults, involves the lower extremity, responds poorly to chemotherapy, and carries a grave prognosis. The authors describe a 12-year-old girl with an extraosseous osteosarcoma of the left sternocleidomastoid muscle with pulmonary metastases. The patient responded well to neoadjuvant chemotherapy and remains disease-free nearly 3 years after her initial diagnosis. The authors review available information about this disease in children and adults. Children with extraosseous osteosarcoma may have a more favorable response to treatment than adults; thus, a curative approach using combined modality therapy appears warranted.

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A chemosensitive pediatric extraosseous osteosarcoma: Case report and review of the literature

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Keywords

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