A brief assessment of concerns associated with genetic testing for cancer: The Multidimensional Impact of Cancer Risk Assessment (MICRA) questionnaire

David Cella, Chanita Hughes, Amy Peterman, Chih Hung Chang, Beth N. Peshkin, Marc D. Schwartz, Lari Wenzel, Amy Lemke, Alfred C. Marcus, Caryn Lerman

Research output: Contribution to journalArticle

158 Scopus citations

Abstract

The Multidimensional Impact of Cancer Risk Assessment (MICRA) is a new tool to measure the specific impact of result disclosure after genetic testing. The authors compared its performance with that of questionnaires measuring general and cancer-specific distress. Participants (158 women) responded 1 month after they received genetic test results. The women were divided into 4 standard clinical test result groups: BRCA1/2 positive, BRCA1/2 negative, panel negative, and true negative. Factor analysis supported the formation of 3 subscales: Distress (6 items, α = .86), Uncertainty (9 items, α = .77), and Positive Experiences (4 items, α = .75). All 3 MICRA subscales differentiated participants who were BRCA 1/2 positive from the other 3 groups. MICRA thus helps identify subgroups of vulnerable genetic testing participants.

Original languageEnglish
Pages (from-to)564-572
Number of pages9
JournalHealth Psychology
Volume21
Issue number6
DOIs
StatePublished - Nov 2002
Externally publishedYes

Keywords

  • Cancer genetics
  • Cancer risk assessment
  • Genetic testing

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    Cella, D., Hughes, C., Peterman, A., Chang, C. H., Peshkin, B. N., Schwartz, M. D., Wenzel, L., Lemke, A., Marcus, A. C., & Lerman, C. (2002). A brief assessment of concerns associated with genetic testing for cancer: The Multidimensional Impact of Cancer Risk Assessment (MICRA) questionnaire. Health Psychology, 21(6), 564-572. https://doi.org/10.1037/0278-6133.21.6.564