Abstract
We treated 10 boys with Duchenne muscular dystrophy with oxandrolone, an anabolic steroid, for 3 months. The mean of the changes in the average muscle score was an improvement of 0.315 ± 0.097. The expected mean change in muscle score after 3 months from natural history data is a loss of 0.1. The difference of 0.415 between the actual and expected values is significant at p < 0.01. This preliminary evidence suggests that oxandrolone treatment may provide a degree of functional benefit for children with Duchenne muscular dystrophy that is similar to that after prednisone administration.
| Original language | English |
|---|---|
| Pages (from-to) | 1225-1226 |
| Number of pages | 2 |
| Journal | Neurology |
| Volume | 48 |
| Issue number | 5 |
| DOIs | |
| State | Published - May 1997 |