A 32-year-old man with hepatitis C who developed progressive liver failure after a bone marrow transplant

Andre C. Lyra, Elizabeth M. Brunt, Steven Pincus, Adrian M. Di Bisceglie

Research output: Contribution to journalArticlepeer-review

Abstract

We describe the case of a 32-year-old man with hepatitis C infection and minimal pre-existing liver injury prior to a bone marrow transplantation, who developed veno-occlusive disease and progressive liver failure posttransplant. A transjugular liver biopsy performed at day 11 after transplantation for ascites and hyperbilirubinemia showed features of veno-occlusive disease. In an effort to control the clinical course, a trans-jugular intrahepatic porto-systemic shunt was placed; thrombolytic therapy with tissue plasminogen activator (t-PA) and antithrombin III was instituted on day 15 post-BMT. The patient did not respond to the therapeutic measures. He expired 25 days after the transplant from pulmonary hemorrhage and liver failure due to hepatic VOD.

Original languageEnglish
Pages (from-to)103-107
Number of pages5
JournalSeminars in Liver Disease
Volume22
Issue number1
DOIs
StatePublished - Mar 25 2002

Fingerprint

Dive into the research topics of 'A 32-year-old man with hepatitis C who developed progressive liver failure after a bone marrow transplant'. Together they form a unique fingerprint.

Cite this