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• SIRT6 is required for normal retinal function

  Silberman, D. M., Ross, K., Sande, P. H., Kubota, S., Ramaswamy, S., Apte, R. S. & Mostoslavsky, R., Jun 4 2014, In: PloS one. 9, 6, e98831.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  46 Scopus citations

• SIRT6 mono-ADP ribosylates KDM2A to locally increase H3K36me2 at DNA damage sites to inhibit transcription and promote repair

  Rezazadeh, S., Yang, D., Biashad, S. A., Firsanov, D., Takasugi, M., Gilbert, M., Tombline, G., Bhanu, N. V., Garcia, B. A., Seluanov, A. & Gorbunova, V., Jun 30 2020, In: Aging. 12, 12, p. 11165-11184 20 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  24 Scopus citations

• SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation

  Barber, M. F., Michishita-Kioi, E., Xi, Y., Tasselli, L., Kioi, M., Moqtaderi, Z., Tennen, R. I., Paredes, S., Young, N. L., Chen, K., Struhl, K., Garcia, B. A., Gozani1, O., Li, W. & Chua, K. F., Jul 2012, In: Nature. 487, 7405, p. 114-118 5 p.

  Research output: Contribution to journal › Article › peer-review
  462 Scopus citations

• Sirtuin1: A Promising Serum Protein Marker for Early Detection of Alzheimer's Disease

  Kumar, R., Chaterjee, P., Sharma, P. K., Singh, A. K., Gupta, A., Gill, K., Tripathi, M., Dey, A. B. & Dey, S., Apr 16 2013, In: PloS one. 8, 4, e61560.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  126 Scopus citations

• Sirtuin 1 (SIRT1) deacetylase activity is not required for mitochondrial biogenesis or peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) deacetylation following endurance exercise

  Philp, A., Chen, A., Lan, D., Meyer, G. A., Murphy, A. N., Knapp, A. E., Olfert, I. M., McCurdy, C. E., Marcotte, G. R., Hogan, M. C., Baar, K. & Schenk, S., Sep 2 2011, In: Journal of Biological Chemistry. 286, 35, p. 30561-30570 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  150 Scopus citations

• Sirtuin 1 agonist minimizes injury and improves the immune response following traumatic shock

  Luciano, J. A., Kautza, B., Darwiche, S., Martinez, S., Stratimirovic, S., Waltz, P., Sperry, J., Rosengart, M., Shiva, S. & Zuckerbraun, B. S., Aug 2015, In: Shock. 44, p. 149-155 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  9 Scopus citations

• Sirtuin 1 mediates protection against delayed cerebral ischemia in subarachnoid hemorrhage in response to hypoxic postconditioning

  Diwan, D., Vellimana, A. K., Aum, D. J., Clarke, J., Nelson, J. W., Lawrence, M., Han, B. H., Gidday, J. M. & Zipfel, G. J., Oct 19 2021, In: Journal of the American Heart Association. 10, 20, e021113.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  15 Scopus citations

• Sirtuin 1 suppresses mitochondrial dysfunction of ischemic mouse livers in a mitofusin 2-dependent manner

  Biel, T. G., Lee, S., Flores-Toro, J. A., Dean, J. W., Go, K. L., Lee, M. H., Law, B. K., Law, M. E., Dunn, W. A., Zendejas, I., Behrns, K. E. & Kim, J. S., Feb 1 2016, In: Cell Death and Differentiation. 23, 2, p. 279-290 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  78 Scopus citations

• Sirtuin 6 and renal injury: another link in the β-catenin chain?

  Gewin, L. S., Jan 2020, In: Kidney International. 97, 1, p. 24-27 4 p.

  Research output: Contribution to journal › Comment/debate
  5 Scopus citations

• Sir-two-homolog 2 (Sirt2) modulates peripheral myelination through polarity protein Par-3/atypical protein kinase C (aPKC) signaling

  Beirowski, B., Gustin, J., Armour, S. M., Yamamoto, H., Viader, A., North, B. J., Michán, S., Baloh, R. H., Golden, J. P., Schmidt, R. E., Sinclair, D. A., Auwerx, J. & Milbrandt, J., Oct 25 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 43, p. E952-E961

  Research output: Contribution to journal › Article › peer-review
  130 Scopus citations

• Sitagliptin, a DPP-4 inhibitor, acutely inhibits intestinal lipoprotein particle secretion in healthy humans

  Xiao, C., Dash, S., Morgantini, C., Patterson, B. W. & Lewis, G. F., Jul 2014, In: Diabetes. 63, 7, p. 2394-2401 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  61 Scopus citations

• Sitagliptin reduces inflammation and chronic immune cell activation in HIV+ adults with impaired glucose tolerance

  Best, C., Struthers, H., Laciny, E., Royal, M., Reeds, D. N. & Yarasheski, K. E., Jul 1 2015, In: Journal of Clinical Endocrinology and Metabolism. 100, 7, p. 2621-2629 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  23 Scopus citations

• Sitagliptin Versus Placebo to Reduce the Incidence and Severity of Posttransplant Diabetes Mellitus After Kidney Transplantation—A Single-center, Randomized, Double-blind Controlled Trial

  Delos Santos, R. B., Hagopian, J. C., Chen, L., Ramakrishnan, M., Wijeweera, H., Klein, C. L. & Brennan, D. C., May 1 2023, In: Transplantation. 107, 5, p. 1180-1187 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Scopus citations

• Site-1 protease ablation in the osterix-lineage in mice results in bone marrow neutrophilia and hematopoietic stem cell alterations

  Patra, D., Kim, J., Zhang, Q., Tycksen, E. & Sandell, L. J., Jun 2020, In: Biology Open. 9, 6, bio052993.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  2 Scopus citations

• Site-1 protease deficiency causes human skeletal dysplasia due to defective inter-organelle protein trafficking

  Kondo, Y., Fu, J., Wang, H., Hoover, C., McDaniel, J. M., Steet, R., Patra, D., Song, J., Pollard, L., Cathey, S., Yago, T., Wiley, G., Macwana, S., Guthridge, J., McGee, S., Li, S., Griffin, C., Furukawa, K., James, J. A., Ruan, C., & 4 othersMcEver, R. P., Wierenga, K. J., Gaffney, P. M. & Xia, L., Jul 26 2018, In: JCI Insight. 3, 14

  Research output: Contribution to journal › Article › peer-review

  Open Access
  32 Scopus citations

• Site-1 protease inhibits mitochondrial respiration by controlling the TGF-β target gene Mss51

  Mousa, M. G., Vuppaladhadiam, L., Kelly, M. O., Pietka, T., Ek, S., Shen, K. C., Meyer, G. A., Finck, B. N. & Brookheart, R. T., Apr 25 2023, In: Cell Reports. 42, 4, 112336.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Site-1 protease is essential for endochondral bone formation in mice

  Patra, D., Xing, X., Davies, S., Bryan, J., Franz, C., Hunziker, E. B. & Sandell, L. J., Nov 19 2007, In: Journal of Cell Biology. 179, 4, p. 687-700 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  51 Scopus citations

• Site-1 protease is essential to growth plate maintenance and is a critical regulator of chondrocyte hypertrophic differentiation in postnatal mice

  Patra, D., DeLassus, E., Hayashi, S. & Sandell, L. J., Aug 19 2011, In: Journal of Biological Chemistry. 286, 33, p. 29227-29240 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  14 Scopus citations

• Site-1 protease regulates skeletal stem cell population and osteogenic differentiation in mice

  Patra, D., DeLassus, E., Mueller, J., Abou-Ezzi, G. & Sandell, L. J., 2018, In: Biology Open. 7, 2, bio032094.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  5 Scopus citations

• Site-directed, virus-free, and inducible RNAi in embryonic stem cells

  Wang, J., Theunissen, T. W. & Orkin, S. H., Dec 26 2007, In: Proceedings of the National Academy of Sciences of the United States of America. 104, 52, p. 20850-20855 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  26 Scopus citations

• Site-directed mutagenesis

  Ishii, T. M., Zerr, P., Xia, X. M., Bond, C. T., Maylie, J. & Adelman, J. P., 1998, In: Methods in enzymology. 293, p. 53-71 19 p.

  Research output: Contribution to journal › Article › peer-review
  38 Scopus citations

• Site-directed mutagenesis defines a domain in the gonadotropin α-subunit required for assembly with the chorionic gonadotropin β-subunit

  Bielinska, M. & Boime, I., Feb 1992, In: Molecular Endocrinology. 6, 2, p. 267-271 5 p.

  Research output: Contribution to journal › Article › peer-review

  39 Scopus citations

• Site-directed mutagenesis identifies amino acid residues associated with the dehydrogenase and isomerase activities of human type I (placental) 3β- hydroxysteroid dehydrogenase/isomerase

  Thomas, J. L., Evans, B. W., Blanco, G., Mercer, R. W., Mason, J. I., Adler, S., Nash, W. E., Isenberg, K. E. & Strickler, R. C., Sep 1998, In: Journal of Steroid Biochemistry and Molecular Biology. 66, 5-6, p. 327-334 8 p.

  Research output: Contribution to journal › Article › peer-review
  34 Scopus citations

• Site-directed mutagenesis in hemoglobin. Effect of some mutations at protein interfaces

  Vallone, B., Vecchini, P., Cavalli, V. & Brunori, M., Jun 14 1993, In: FEBS Letters. 324, 2, p. 117-122 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  9 Scopus citations

• Site-directed mutagenesis of arginine 103 and lysine 185 in the proposed glycosaminoglycan-binding site of heparin cofactor II

  Blinder, M. A. & Tollefsen, D. M., Jan 5 1990, In: Journal of Biological Chemistry. 265, 1, p. 286-291 6 p.

  Research output: Contribution to journal › Article › peer-review

  53 Scopus citations

• Site-directed mutagenesis of cys-15 and cys-20 of pulmonary surfactant protein D: Expression of a trimeric protein with altered anti-viral properties

  Brown-Augsburger, P., Hartshorn, K., Chang, D., Rust, K., Fliszar, C., Welgus, H. G. & Crouch, E. C., 1996, In: Journal of Biological Chemistry. 271, 23, p. 13724-13730 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  119 Scopus citations

• Site directed mutagenesis of the heme axial ligands of cytochrome b559 affects the stability of the photosystem II complex

  Pakrasi, H. B., De Ciechi, P. & Whitmarsh, J., 1991, In: EMBO Journal. 10, 7, p. 1619-1627 9 p.

  Research output: Contribution to journal › Article › peer-review

  82 Scopus citations

• Site-Directed Mutagenesis of κ-Bungarotoxin: Implications for Neuronal Receptor Specificity

  Fiordalisi, J. J., Al-Rabiee, R., Grant, G. A. & Chiappinelli, V. A., Apr 1 1994, In: Biochemistry. 33, 13, p. 3872-3877 6 p.

  Research output: Contribution to journal › Article › peer-review
  26 Scopus citations

• Site-directed mutagenesis within an ectoplasmic ATPase consensus sequence abrogates the cell aggregating properties of the rat liver canalicular bile acid transporter/ecto-ATPase/cell CAM 105 and carcinoembryonic antigen

  Sippel, C. J., Shen, T. & Perlmutter, D. H., 1996, In: Journal of Biological Chemistry. 271, 51, p. 33095-33104 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  17 Scopus citations

• Site-directed spectroscopic probes of actomyosin structural dynamics

  Thomas, D. D., Kast, D. & Korman, V. L., 2009, In: Annual Review of Biophysics. 38, 1, p. 347-369 23 p.

  Research output: Contribution to journal › Review article › peer-review
  43 Scopus citations

• Site-Level Bioactivity of Small-Molecules from Deep-Learned Representations of Quantum Chemistry

  Sarullo, K., Matlock, M. K. & Swamidass, S. J., Nov 5 2020, In: Journal of Physical Chemistry A. 124, 44, p. 9194-9202 9 p.

  Research output: Contribution to journal › Article › peer-review
  5 Scopus citations

• Site of action of anorectic drugs: Glucoprivic- versus food deprivation-induced feeding

  Angel, I., Stivers, J. A., Paul, S. M. & Crawley, J. N., Jun 1987, In: Pharmacology, Biochemistry and Behavior. 27, 2, p. 291-297 7 p.

  Research output: Contribution to journal › Article › peer-review
  10 Scopus citations

• Site of reactivity models predict molecular reactivity of diverse chemicals with glutathione

  Hughes, T. B., Miller, G. P. & Swamidass, S. J., Apr 20 2015, In: Chemical Research in Toxicology. 28, 4, p. 797-809 13 p.

  Research output: Contribution to journal › Article › peer-review
  68 Scopus citations

• Sites Contributing to TRPA1 Activation by the Anesthetic Propofol Identified by Photoaffinity Labeling

  Woll, K. A., Skinner, K. A., Gianti, E., Bhanu, N. V., Garcia, B. A., Carnevale, V., Eckenhoff, R. G. & Gaudet, R., Nov 21 2017, In: Biophysical Journal. 113, 10, p. 2168-2172 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  24 Scopus citations

• Site-selective, cleavable linkers: Quality control and the characterization of small molecules on microelectrode arrays

  Bi, B., Huang, R. Y. C., Maurer, K., Chen, C. & Moeller, K. D., Nov 4 2011, In: Journal of Organic Chemistry. 76, 21, p. 9053-9059 7 p.

  Research output: Contribution to journal › Article › peer-review
  13 Scopus citations

• Site-selective chemistry and the attachment of peptides to the surface of a microelectrode array

  Fellet, M. S., Bartels, J. L., Bi, B. & Moeller, K. D., Oct 10 2012, In: Journal of the American Chemical Society. 134, 40, p. 16891-16898 8 p.

  Research output: Contribution to journal › Article › peer-review
  23 Scopus citations

• Site selective C–H functionalization of Mitragyna alkaloids reveals a molecular switch for tuning opioid receptor signaling efficacy

  Bhowmik, S., Galeta, J., Havel, V., Nelson, M., Faouzi, A., Bechand, B., Ansonoff, M., Fiala, T., Hunkele, A., Kruegel, A. C., Pintar, J. E., Majumdar, S., Javitch, J. A. & Sames, D., Dec 1 2021, In: Nature communications. 12, 1, 3858.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  21 Scopus citations

• Site-selectively functionalizing microelectrode arrays: The use of Cu(I)-catalysts

  Bartels, J., Lu, P., Maurer, K., Walker, A. V. & Moeller, K. D., Sep 6 2011, In: Langmuir. 27, 17, p. 11199-11205 7 p.

  Research output: Contribution to journal › Article › peer-review
  29 Scopus citations

• Sites of action of diphenylhydantoin in experimental seizures.

  Louis, S., Kutt, H., Raichle, M. & McDowell, F., Dec 1 1969, In: Transactions of the American Neurological Association. 94, p. 195-198 4 p.

  Research output: Contribution to journal › Article › peer-review

• Sites of core-specific lectin assembly

  Colley, K. J. & Baenziger, J. U., Jan 1 1984, In: Federation proceedings. 43, 7, p. no. 3652

  Research output: Contribution to journal › Article › peer-review

• Sites of RNA polymerase III transcription initiation and Ty3 integration at the U6 gene are positioned by the TATA box

  Chalker, D. L. & Sandmeyer, S. B., Jun 1 1993, In: Proceedings of the National Academy of Sciences of the United States of America. 90, 11, p. 4927-4931 5 p.

  Research output: Contribution to journal › Article › peer-review

  35 Scopus citations

• Sites of rupture in human atherosclerotic carotid plaques are associated with high structural stresses: An in Vivo MRI-based 3D fluid-structure interaction study

  Tang, D., Teng, Z., Canton, G., Yang, C., Ferguson, M., Huang, X., Zheng, J., Woodard, P. K. & Yuan, C., Oct 2009, In: Stroke. 40, 10, p. 3258-3263 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  175 Scopus citations

• Site-specific basal body duplication in Chlamydomonas

  O'Toole, E. T. & Dutcher, S. K., Feb 2014, In: Cytoskeleton. 71, 2, p. 108-118 11 p.

  Research output: Contribution to journal › Article › peer-review
  41 Scopus citations

• Site-specific casein kinase 1ε-dependent phosphorylation of Dishevelled modulates β-catenin signaling

  Klimowski, L. K., Garcia, B. A., Shabanowitz, J., Hunt, D. F. & Virshup, D. M., Oct 2006, In: FEBS Journal. 273, 20, p. 4594-4602 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  36 Scopus citations

• Site-Specific Cerebrospinal Fluid Tau Hyperphosphorylation in Response to Alzheimer's Disease Brain Pathology: Not All Tau Phospho-Sites are Hyperphosphorylated

  Barthélemy, N. R., Toth, B., Manser, P. T., Sanabria-Bohórquez, S., Teng, E., Keeley, M., Bateman, R. J., Weimer, R. M. & Wildsmith, K. R., 2022, In: Journal of Alzheimer's Disease. 85, 1, p. 415-429 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  6 Scopus citations

• Site-specific dissection of substrate recognition by Thrombin

  Vindigni, A., Dang, Q. D. & Cera, E. D., Sep 1997, In: Nature Biotechnology. 15, 9, p. 891-895 5 p.

  Research output: Contribution to journal › Article › peer-review
  64 Scopus citations

• Site-specific effect of thymine dimer formation on dA_n·dT_n tract bending and its biological implications

  Wang, C. I. & Taylor, J. S., Oct 15 1991, In: Proceedings of the National Academy of Sciences of the United States of America. 88, 20, p. 9072-9076 5 p.

  Research output: Contribution to journal › Article › peer-review

  100 Scopus citations

• Site-specific effects of compression on macromolecular diffusion in articular cartilage

  Leddy, H. A. & Guilak, F., Nov 15 2008, In: Biophysical Journal. 95, 10, p. 4890-4895 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  36 Scopus citations

• Site-specific effects of neurosteroids on gaba_a receptor activation and desensitization

  Sugasawa, Y., Cheng, W. W. L., Bracamontes, J. R., Chen, Z. W., Wang, L., Germann, A. L., Pierce, S. R., Senneff, T. C., Krishnan, K., Reichert, D. E., Covey, D. F., Akk, G. & Evers, A. S., Sep 2020, In: eLife. 9, p. 1-32 32 p., e55331.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  28 Scopus citations

• Site-specific experiments on folding/unfolding of Jun coiled coils: Thermodynamic and kinetic parameters from spin inversion transfer nuclear magnetic resonance at leucine-18

  D'Avignon, D. A., Bretthorst, G. L., Holtzer, M. E., Schwarz, K. A., Angeletti, R. H., Mints, L. & Holtzer, A., Oct 15 2006, In: Biopolymers. 83, 3, p. 255-267 13 p.

  Research output: Contribution to journal › Article › peer-review
  7 Scopus citations