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• Structure and function of the mannose 6-phosphate/insulinlike growth factor II receptors

  Kornfeld, S., 1992, In: Annual review of biochemistry. 61, p. 307-330 24 p.

  Research output: Contribution to journal › Review article › peer-review
  941 Scopus citations

• Structure and function of the murine β-globin locus control region 5′ HS-3

  Hug, B. A., Moon, A. M. & Ley, T. J., Nov 11 1992, In: Nucleic acids research. 20, 21, p. 5771-5778 8 p.

  Research output: Contribution to journal › Article › peer-review
  57 Scopus citations

• Structure and function of the Smoothened extracellular domain in vertebrate Hedgehog signaling

  Nachtergaele, S., Whalen, D. M., Mydock, L. K., Zhao, Z., Malinauskas, T., Krishnan, K., Ingham, P. W., Covey, D. F., Siebold, C. & Rohatgi, R., Oct 29 2013, In: eLife. 2013, 2, e01340.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  115 Scopus citations

• Structure and inhibition of plasmepsin II, a hemoglobin-degrading enzyme from Plasmodium falciparum

  Silva, A. M., Lee, A. Y., Gulnik, S. V., Majer, P., Collins, J., Bhat, T. N., Collins, P. J., Cachau, R. E., Luker, K. E., Gluzman, I. Y., Francis, S. E., Oksman, A., Goldberg, D. E. & Erickson, J. W., Sep 17 1996, In: Proceedings of the National Academy of Sciences of the United States of America. 93, 19, p. 10034-10039 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  274 Scopus citations

• Structure and intracellular targeting of the SARS-coronavirus orf7a accessory protein

  Nelson, C. A., Pekosz, A., Lee, C. A., Diamond, M. S. & Fremont, D. H., Jan 2005, In: Structure. 13, 1, p. 75-85 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  121 Scopus citations

• Structure and IR spectrum of phenylalanyl-glycyl-glycine tripetide in the gas-phase: IR/UV experiments, Ab initio quantum chemical calculations, and molecular dynamic simulations

  Řeha, D., Valdés, H., Vondrášek, J., Hobza, P., Abu-Riziq, A., Crews, B. & De Vries, M. S., Nov 18 2005, In: Chemistry - A European Journal. 11, 23, p. 6803-6817 15 p.

  Research output: Contribution to journal › Article › peer-review
  159 Scopus citations

• Structure and ligand recognition of the phosphotyrosine binding domain of Shc

  Zhou, M. M., Ravichandran, K. S., Olejniczak, E. T., Petros, A. M., Meadows, R. P., Sattler, M., Harlan, J. E., Wade, W. S., Burakoff, S. J. & Fesik, S. W., Dec 7 1995, In: Nature. 378, 6557, p. 584-592 9 p.

  Research output: Contribution to journal › Article › peer-review
  325 Scopus citations

• Structure and lipophilicity - The keys to understanding the function of pyruvate derivatives for ischemia/reperfusion?

  Abarbanell, A. M., Nov 2010, In: Journal of Surgical Research. 164, 1, p. 72-73 2 p.

  Research output: Contribution to journal › Comment/debate
  1 Scopus citations

• Structure and mapping of the G protein γ3 subunit gene and a divergently transcribed novel gene, Gng3lg

  Downes, G. B., Copeland, N. G., Jenkins, N. A. & Gautam, N., Oct 15 1998, In: Genomics. 53, 2, p. 220-230 11 p.

  Research output: Contribution to journal › Article › peer-review
  28 Scopus citations

• Structure and mechanism of ferulic acid decarboxylase (FDC1) from saccharomyces cerevisiae

  Bhuiya, M. W., Lee, S. G., Jez, J. M. & Yu, O., 2015, In: Applied and Environmental Microbiology. 81, 12, p. 4216-4223 8 p.

  Research output: Contribution to journal › Article › peer-review
  26 Scopus citations

• Structure and mechanism of isopropylmalate dehydrogenase from Arabidopsis thaliana: Insights on leucine and aliphatic glucosinolate biosynthesis

  Lee, S. G., Nwumeh, R. & Jez, J. M., Jun 24 2016, In: Journal of Biological Chemistry. 291, 26, p. 13421-13430 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  11 Scopus citations

• Structure and mechanism of mouse cyclase-associated protein (CAP1) in regulating actin dynamics

  Jansen, S., Collins, A., Golden, L., Sokolova, O. & Goode, B. L., Oct 31 2014, In: Journal of Biological Chemistry. 289, 44, p. 30732-30742 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  43 Scopus citations

• Structure and Mechanism of Plant DNA Methyltransferases

  Leichter, S. M., Du, J. & Zhong, X., 2022, Advances in Experimental Medicine and Biology. Springer, p. 137-157 21 p. (Advances in Experimental Medicine and Biology; vol. 1389).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

• Structure and mechanism of soybean ATP sulfurylase and the committed step in plant sulfur assimilation

  Herrmann, J., Ravilious, G. E., McKinney, S. E., Westfall, C. S., Lee, S. G., Baraniecka, P., Giovannetti, M., Kopriva, S., Krishnan, H. B. & Jez, J. M., Apr 11 2014, In: Journal of Biological Chemistry. 289, 15, p. 10919-10929 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  36 Scopus citations

• Structure and mechanism of the evolutionarily unique plant enzyme chalcone isomerase

  Jez, J. M., Bowman, M. E., Dixon, R. A. & Noel, J. P., Sep 2000, In: Nature Structural Biology. 7, 9, p. 786-791 6 p.

  Research output: Contribution to journal › Article › peer-review
  282 Scopus citations

• Structure and medium effects on hydraphile synthetic ion channel toxicity to the bacterium E. coli

  Leevy, W. M., Gokel, M. R., Hughes-Strange, G. B., Schlesinger, P. H. & Gokel, G. W., Jan 2005, In: New Journal of Chemistry. 29, 1, p. 205-209 5 p.

  Research output: Contribution to journal › Article › peer-review
  20 Scopus citations

• Structure and noncanonical Cdk8 activation mechanism within an Argonaute-containing Mediator kinase module

  Li, Y. C., Chao, T. C., Kim, H. J., Cholko, T., Chen, S. F., Li, G., Snyder, L., Nakanishi, K., Chang, C. E., Murakami, K., Garcia, B. A., Boyer, T. G. & Tsai, K. L., Jan 15 2021, In: Science Advances. 7, 3, eabd4484.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  23 Scopus citations

• Structure and organization of membrane organelles along distal microtubule segments in growth cones

  Dailey, M. E. & Bridgman, P. C., Sep 1991, In: Journal of Neuroscience Research. 30, 1, p. 242-258 17 p.

  Research output: Contribution to journal › Article › peer-review
  35 Scopus citations

• Structure and physiological function of the human KCNQ1 channel voltage sensor intermediate state

  Taylor, K. C., Kang, P. W., Hou, P., Yang, N. D., Kuenze, G., Smith, J. A., Shi, J., Huang, H., White, K. M., Peng, D., George, A. L., Meiler, J., McFeeters, R. L., Cui, J. & Sanders, C. R., Feb 2020, In: eLife. 9, e53901.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  22 Scopus citations

• Structure and processivity of two forms of saccharomyces cerevisiae DNA polymerase δ

  Burgers, P. M. J. & Gerik, K. J., Jul 31 1998, In: Journal of Biological Chemistry. 273, 31, p. 19756-19762 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  165 Scopus citations

• Structure and properties of DNA photoproducts

  Taylor, J. S., Sep 9 2005, Separation Methods In Microanalytical Systems. CRC Press, p. 67-94 28 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

• Structure and Properties of DNA Photoproducts

  Taylor, J. S., Jan 1 2005, DNA Damage Recognition. CRC Press, p. 67-94 28 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
  7 Scopus citations

• Structure and reaction mechanism of phosphoethanolamine methyltransferase from the malaria parasite Plasmodium falciparum: An antiparasitic drug target

  Lee, S. G., Kim, Y., Alpert, T. D., Nagata, A. & Jez, J. M., Jan 6 2012, In: Journal of Biological Chemistry. 287, 2, p. 1426-1434 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  45 Scopus citations

• Structure and regulatory profile of the monkeypox inhibitor of complement: Comparison to homologs in vaccinia and variola and evidence for dimer formation

  Liszewski, M. K., Leung, M. K., Hauhart, R., Buller, R. M. L., Bertram, P., Wang, X., Rosengard, A. M., Kotwal, G. J. & Atkinson, J. P., Mar 15 2006, In: Journal of Immunology. 176, 6, p. 3725-3734 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  88 Scopus citations

• Structure and sequence of human M/NEI (monocyte/neutrophil elastase inhibitor), an Ov-serpin family gene

  Zeng, W., Silverman, G. A. & Remold-O'Donnell, E., Jun 15 1998, In: Gene. 213, 1-2, p. 179-187 9 p.

  Research output: Contribution to journal › Article › peer-review
  15 Scopus citations

• Structure and sequence of the chicken type II procollagen gene. Characterization of the region encoding the carboxyl-terminal telopeptide and propeptide

  Sandell, L. J., Prentice, H. L., Kravis, D. & Upholt, W. B., 1984, In: Journal of Biological Chemistry. 259, 12, p. 7826-7834 9 p.

  Research output: Contribution to journal › Article › peer-review

  37 Scopus citations

• Structure and specificity of GATA proteins in Th2 development

  Ranganath, S. & Murphy, K. M., 2001, In: Molecular and cellular biology. 21, 8, p. 2716-2725 10 p.

  Research output: Contribution to journal › Article › peer-review
  63 Scopus citations

• Structure and Spectroscopy of Copper-Dioxygen Complexes

  Mirica, L. M., Ottenwaelder, X. & Stack, T. D. P., Feb 2004, In: Chemical Reviews. 104, 2, p. 1013-1045 33 p.

  Research output: Contribution to journal › Review article › peer-review
  1172 Scopus citations

• STRUCTURE AND STABILITY OF CHILDHOOD PERSONALITY: PREDICTION OF LATER SOCIAL ADJUSTMENT

  Sigvardsson, S., Bohman, M. & Cloninger, C. R., Nov 1987, In: Journal of Child Psychology and Psychiatry. 28, 6, p. 929-946 18 p.

  Research output: Contribution to journal › Article › peer-review
  74 Scopus citations

• Structure and stability of RNA/RNA kissing complex: With application to HIV dimerization initiation signal

  Cao, S. & Chen, S. J., Dec 2011, In: RNA. 17, 12, p. 2130-2143 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  35 Scopus citations

• Structure and synthesis of a potent glutamate receptor antagonist in wasp venom.

  Eldefrawi, A. T., Eldefrawi, M. E., Konno, K., Mansour, N. A., Nakanishi, K., Oltz, E. & Usherwood, P. N., Jul 1988, In: Proceedings of the National Academy of Sciences of the United States of America. 85, 13, p. 4910-4913 4 p.

  Research output: Contribution to journal › Article › peer-review
  209 Scopus citations

• Structure and transcriptional regulation of the human mammaglobin gene, a breast cancer associated member of the uteroglobin gene family localized to Chromosome 11q13

  Watson, M. A., Darrow, C., Zimonjic, D. B., Popescu, N. C. & Fleming, T. P., Feb 12 1998, In: Oncogene. 16, 6, p. 817-824 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  84 Scopus citations

• Structure and Ubiquitination-Dependent Activation of TANK-Binding Kinase 1

  Tu, D., Zhu, Z., Zhou, A. Y., Yun, C. H., Lee, K. E., Toms, A. V., Li, Y., Dunn, G. P., Chan, E., Thai, T., Yang, S., Ficarro, S. B., Marto, J. A., Jeon, H., Hahn, W. C., Barbie, D. A. & Eck, M. J., 2013, In: Cell Reports. 3, 3, p. 747-758 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  142 Scopus citations

• Structure and Uncoating of Immature Adenovirus

  Pérez-Berná, A. J., Marabini, R., Scheres, S. H. W., Menéndez-Conejero, R., Dmitriev, I. P., Curiel, D. T., Mangel, W. F., Flint, S. J. & Martín, C. S., Sep 18 2009, In: Journal of Molecular Biology. 392, 2, p. 547-557 11 p.

  Research output: Contribution to journal › Article › peer-review
  63 Scopus citations

• Structure-based approach to the photocontrol of protein folding

  Zhang, F., Zarrine-Afsar, A., Al-Abdul-Wahid, M. S., Prosser, R. S., Davidson, A. R. & Woolley, G. A., Feb 18 2009, In: Journal of the American Chemical Society. 131, 6, p. 2283-2289 7 p.

  Research output: Contribution to journal › Article › peer-review
  84 Scopus citations

• Structure-based design and synthesis of conformationally constrained derivatives of methyl-piperidinopyrazole (MPP) with estrogen receptor (ER) antagonist activity

  Ragab, M. A., Elagawany, M., Daabees, H., Ahmed, A. S. F., Awad, E. M., Billon, C., Elgendy, B., Abouzid, K. A. M. & Kassab, S. E., Feb 2022, In: Bioorganic Chemistry. 119, 105554.

  Research output: Contribution to journal › Article › peer-review
  3 Scopus citations

• Structure based design and synthesis of peptide inhibitor of human lox-12: In vitro and in vivo analysis of a novel therapeutic agent for breast cancer

  Singh, A. K., Singh, R., Naz, F., Chauhan, S. S., Dinda, A., Shukla, A. A., Gill, K., Kapoor, V. & Dey, S., Feb 23 2012, In: PloS one. 7, 2, e32521.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  21 Scopus citations

• Structure-based design and synthesis of triazole-based macrocyclic inhibitors of norovirus protease: Structural, biochemical, spectroscopic, and antiviral studies

  Weerawarna, P. M., Kim, Y., Kankanamalage, A. C. G., Damalanka, V. C., Lushington, G. H., Alliston, K. R., Mehzabeen, N., Battaile, K. P., Lovell, S., Chang, K. O. & Groutas, W. C., 2016, In: European Journal of Medicinal Chemistry. 119, p. 300-318 19 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  27 Scopus citations

• Structure-based design of benzo[e]isoindole-1,3-dione derivatives as selective GSK-3β inhibitors to activate Wnt/β-catenin pathway

  Yue, H., Lu, F., Shen, C. & Quan, J. M., Jun 11 2015, In: Bioorganic Chemistry. 61, p. 21-27 7 p.

  Research output: Contribution to journal › Article › peer-review
  20 Scopus citations

• Structure-Based Design of Bisubstrate Tetracycline Destructase Inhibitors That Block Flavin Redox Cycling

  Williford, E. E., DeAngelo, C. M., Blake, K. S., Kumar, H., Lam, K. K., Jones, K. V., Tolia, N. H., Dantas, G. & Wencewicz, T. A., Mar 23 2023, In: Journal of Medicinal Chemistry. 66, 6, p. 3917-3933 17 p.

  Research output: Contribution to journal › Article › peer-review
  1 Scopus citations

• Structure-based design of bitopic ligands for the µ-opioid receptor

  Faouzi, A., Wang, H., Zaidi, S. A., DiBerto, J. F., Che, T., Qu, Q., Robertson, M. J., Madasu, M. K., El Daibani, A., Varga, B. R., Zhang, T., Ruiz, C., Liu, S., Xu, J., Appourchaux, K., Slocum, S. T., Eans, S. O., Cameron, M. D., Al-Hasani, R., Pan, Y. X., & 6 othersRoth, B. L., McLaughlin, J. P., Skiniotis, G., Katritch, V., Kobilka, B. K. & Majumdar, S., Jan 26 2023, In: Nature. 613, 7945, p. 767-774 8 p.

  Research output: Contribution to journal › Article › peer-review
  9 Scopus citations

• Structure-based design of estrogen-related receptors modulators

  Goher, S. S. & Elgendy, B., Sep 28 2021, Nuclear Receptors: The Art and Science of Modulator Design and Discovery. Springer International Publishing, p. 79-109 31 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
  2 Scopus citations

• Structure-based discovery of glycomimetic FmlH ligands as inhibitors of bacterial adhesion during urinary tract infection

  Kalas, V., Hibbing, M. E., Maddirala, A. R., Chugani, R., Pinkner, J. S., Mydock-McGrane, L. K., Conover, M. S., Janetka, J. W. & Hultgren, S. J., Mar 20 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 12, p. E2819-E2828

  Research output: Contribution to journal › Article › peer-review

  Open Access
  63 Scopus citations

• Structure-based discovery of small molecule hepsin and HGFA protease inhibitors: Evaluation of potency and selectivity derived from distinct binding pockets

  Franco, F. M., Jones, D. E., Harris, P. K. W., Han, Z., Wildman, S. A., Jarvis, C. M. & Janetka, J. W., May 15 2015, In: Bioorganic and Medicinal Chemistry. 23, 10, p. 2328-2343 16 p.

  Research output: Contribution to journal › Article › peer-review
  25 Scopus citations

• Structure-based drug design and optimization of mannoside bacterial fimH antagonists

  Han, Z., Pinkner, J. S., Ford, B., Obermann, R., Nolan, W., Wildman, S. A., Hobbs, D., Ellenberger, T., Cusumano, C. K., Hultgren, S. J. & Janetka, J. W., Jun 24 2010, In: Journal of Medicinal Chemistry. 53, 12, p. 4779-4792 14 p.

  Research output: Contribution to journal › Article › peer-review
  206 Scopus citations

• Structure-based drug design of pyrazinone antithrombotics as selective inhibitors of the tissue factor VIIa complex

  South, M. S., Case, B. L., Wood, R. S., Jones, D. E., Hayes, M. J., Girard, T. J., Lachance, R. M., Nicholson, N. S., Clare, M., Stevens, A. M., Stegeman, R. A., Stallings, W. C., Kurumbail, R. G. & Parlow, J. J., Jul 21 2003, In: Bioorganic and Medicinal Chemistry Letters. 13, 14, p. 2319-2325 7 p.

  Research output: Contribution to journal › Article › peer-review
  58 Scopus citations

• Structure-based exploration and exploitation of the S₄subsite of norovirus 3CL protease in the design of potent and permeable inhibitors

  Galasiti Kankanamalage, A. C., Kim, Y., Rathnayake, A. D., Damalanka, V. C., Weerawarna, P. M., Doyle, S. T., Alsoudi, A. F., Dissanayake, D. M. P., Lushington, G. H., Mehzabeen, N., Battaile, K. P., Lovell, S., Chang, K. O. & Groutas, W. C., 2017, In: European Journal of Medicinal Chemistry. 126, p. 502-516 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  15 Scopus citations

• Structure-based inhibitor design of AccD5, an essential acyl-CoA carboxylase carboxyltransferase domain of Mycobacterium tuberculosis

  Lin, T. W., Melgar, M. M., Kurth, D., Swamidass, S. J., Purdon, J., Tseng, T., Gago, G., Baldi, P., Gramajo, H. & Tsai, S. C., Feb 28 2006, In: Proceedings of the National Academy of Sciences of the United States of America. 103, 9, p. 3072-3077 6 p.

  Research output: Contribution to journal › Article › peer-review
  98 Scopus citations

• Structure-based mapping of DAF active site residues that accelerate the decay of C3 convertases

  Kuttner-Kondo, L., Hourcade, D. E., Anderson, V. E., Muqim, N., Mitchell, L., Soares, D. C., Barlow, P. N. & Medof, M. E., Jun 22 2007, In: Journal of Biological Chemistry. 282, 25, p. 18552-18562 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  23 Scopus citations

• Structure binding relationship of human surfactant protein D and various lipopolysaccharide inner core structures

  Reinhardt, A., Wehle, M., Geissner, A., Crouch, E. C., Kang, Y., Yang, Y., Anish, C., Santer, M. & Seeberger, P. H., Sep 1 2016, In: Journal of Structural Biology. 195, 3, p. 387-395 9 p.

  Research output: Contribution to journal › Article › peer-review
  16 Scopus citations