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• Targeted Delivery of Immunomodulators to Lymph Nodes

  Azzi, J., Yin, Q., Uehara, M., Ohori, S., Tang, L., Cai, K., Ichimura, T., McGrath, M., Maarouf, O., Kefaloyianni, E., Loughhead, S., Petr, J., Sun, Q., Kwon, M., Tullius, S., von Andrian, U. H., Cheng, J. & Abdi, R., May 10 2016, In: Cell Reports. 15, 6, p. 1202-1213 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  63 Scopus citations

• Targeted delivery of siRNA to cell death proteins in sepsis

  Brahmamdam, P., Watanabe, E., Unsinger, J., Chang, K. C., Schierding, W., Hoekzema, A. S., Zhou, T. T., McDonough, J. S., Holemon, H., Heidel, J. D., Coopersmith, C. M., McDunn, J. E. & Hotchkiss, R. S., Aug 2009, In: Shock. 32, 2, p. 131-139 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  9 Scopus citations

• Targeted detection of genetic alterations reveal the prognostic impact of H3K27M and MAPK pathway aberrations in paediatric thalamic glioma

  Ryall, S., Krishnatry, R., Arnoldo, A., Buczkowicz, P., Mistry, M., Siddaway, R., Ling, C., Pajovic, S., Yu, M., Rubin, J. B., Hukin, J., Steinbok, P., Bartels, U., Bouffet, E., Tabori, U. & Hawkins, C., Aug 31 2016, In: Acta Neuropathologica Communications. 4, 1, p. 93 1 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  79 Scopus citations

• Targeted discovery of novel human exons by comparative genomics

  Siepel, A., Diekhans, M., Brejová, B., Langton, L., Stevens, M., Comstock, C. L. G., Davis, C., Ewing, B., Oommen, S., Lau, C., Yu, H. C., Li, J., Roe, B. A., Green, P., Gerhard, D. S., Temple, G., Haussler, D. & Brent, M. R., Dec 2007, In: Genome research. 17, 12, p. 1763-1773 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  38 Scopus citations

• Targeted discovery of polycyclic tetramate macrolactams from an environmental Streptomyces strain

  Cao, S., Blodgett, J. A. V. & Clardy, J., Oct 15 2010, In: Organic Letters. 12, 20, p. 4652-4654 3 p.

  Research output: Contribution to journal › Article › peer-review
  54 Scopus citations

• Targeted disruption of fibulin-4 abolishes elastogenesis and causes perinatal lethality in mice

  McLaughlin, P. J., Chen, Q., Horiguchi, M., Starcher, B. C., Stanton, J. B., Broekelmann, T. J., Marmorstein, A. D., McKay, B., Mecham, R., Nakamura, T. & Marmorstein, L. Y., Mar 2006, In: Molecular and cellular biology. 26, 5, p. 1700-1709 10 p.

  Research output: Contribution to journal › Article › peer-review
  172 Scopus citations

• Targeted disruption of the Cln3 gene provides a mouse model for Batten disease

  Mitchison, H. M., Bernard, D. J., Greene, N. D. E., Cooper, J. D., Junaid, M. A., Pullarkat, R. K., De Vos, N., Breuning, M. H., Owens, J. W., Mobley, W. C., Gardiner, R. M., Lake, B. D., Taschner, P. E. M. & Nussbaum, R. L., Oct 1999, In: Neurobiology of Disease. 6, 5, p. 321-334 14 p.

  Research output: Contribution to journal › Article › peer-review
  81 Scopus citations

• Targeted disruption of the GRA2 locus in Toxoplasma gondii decreases acute virulence in mice

  Mercier, C., Howe, D. K., Mordue, D., Lingnau, M. & Sibley, L. D., 1998, In: Infection and immunity. 66, 9, p. 4176-4182 7 p.

  Research output: Contribution to journal › Article › peer-review
  89 Scopus citations

• Targeted disruption of the mouse apobec-1 gene abolishes apolipoprotein B mRNA editing and eliminates apolipoprotein B48

  Hirano, K. I., Young, S. G., Farese, R. V., Ng, J., Sande, E., Warburton, C., Powell-Braxton, L. M. & Davidson, N. O., Apr 26 1996, In: Journal of Biological Chemistry. 271, 17, p. 9887-9890 4 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  28 Scopus citations

• Targeted disruption of the murine tissue factor gene results in embryonic lethality

  Toomey, J. R., Kratzer, K. E., Lasky, N. M., Stanton, J. J. & Broze, G. J., Sep 1 1996, In: Blood. 88, 5, p. 1583-1587 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  233 Scopus citations

• Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway

  Meraz, M. A., White, J. M., Sheehan, K. C. F., Bach, E. A., Rodig, S. J., Dighe, A. S., Kaplan, D. H., Riley, J. K., Greenlund, A. C., Campbell, D., Carver-Moore, K., DuBois, R. N., Clark, R., Aguet, M. & Schreiber, R. D., Feb 9 1996, In: Cell. 84, 3, p. 431-442 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  357 Scopus citations

• Targeted disruption β-catenin in Sf1-expressing cells impairs development and maintenance of the adrenal cortex

  Kim, A. C., Reuter, A. L., Zubair, M., Else, T., Serecky, K., Bingham, N. C., Lavery, G. G., Parker, K. L. & Hammer, G. D., Aug 2008, In: Development. 135, 15, p. 2593-2602 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  39 Scopus citations

• Targeted endometrial cancer therapy as a future prospect

  Thanapprapasr, D., Cheewakriangkrai, C., Likittanasombut, P., Thanapprapasr, K. & Mutch, D. G., Mar 2013, In: Women's Health. 9, 2, p. 189-199 11 p.

  Research output: Contribution to journal › Review article › peer-review
  9 Scopus citations

• Targeted epigenetic repression of a lymphoma oncogene by sequence-specific histone modifiers induces apoptosis in DLBCL

  Luo, H., Schmidt, J. A., Lee, Y. S., Oltz, E. M. & Payton, J. E., Feb 1 2017, In: Leukemia and Lymphoma. 58, 2, p. 445-456 12 p.

  Research output: Contribution to journal › Article › peer-review
  2 Scopus citations

• Targeted eradication of ovarian cancer mediated by intracellular expression of anti-erbb-2 single-chain antibody

  Deshane, J., Cabrera, G., Grim, J. E., Siegal, G. P., Pike, J., Alvarez, R. D. & Curiel, D. T., Oct 1995, In: Gynecologic oncology. 59, 1, p. 8-14 7 p.

  Research output: Contribution to journal › Article › peer-review
  55 Scopus citations

• Targeted Exome Sequencing Integrated with Clinicopathological Information Reveals Novel and Rare Mutations in Atypical, Suspected and Unknown Cases of Alport Syndrome or Proteinuria

  Chatterjee, R., Hoffman, M., Cliften, P., Seshan, S., Liapis, H. & Jain, S., Oct 10 2013, In: PloS one. 8, 10, e76360.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  50 Scopus citations

• Targeted expression of a dominant-negative K(v)4.2 K⁺ channel subunit in the mouse heart

  Wickenden, A. D., Lee, P., Sah, R., Huang, Q., Fishman, G. I. & Backx, P. H., Nov 26 1999, In: Circulation research. 85, 11, p. 1067-1076 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  103 Scopus citations

• Targeted expression of a dominant-negative N-cadherin in vivo delays peak bone mass and increases adipogenesis

  Castro, C. H. M., Shin, C. S., Stains, J. P., Cheng, S. L., Sheikh, S., Mbalaviele, G., Szejnfeld, V. L. & Civitelli, R., Jun 1 2004, In: Journal of cell science. 117, 13, p. 2853-2864 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  45 Scopus citations

• Targeted expression of BCL-2 attenuates MPP⁺ but not 6-OHDA induced cell death in dopaminergic neurons

  O'Malley, K. L., Liu, J., Lotharius, J. & Holtz, W., Oct 2003, In: Neurobiology of Disease. 14, 1, p. 43-51 9 p.

  Research output: Contribution to journal › Article › peer-review
  46 Scopus citations

• Targeted expression of cloned genes in transgenic mice

  MacDonald, R. J., Swift, G. H., Hammer, R. E., Ornitz, D. M., Davis, B. P., Brinster, R. L. & Palmiter, R. D., Jan 1987, In: Progress in Brain Research. 71, C, p. 3-12 10 p.

  Research output: Contribution to journal › Article › peer-review

• Targeted expression of cloned genes to the pancreas of transgenic mice

  MacDonald, R. J., Swift, G. H. & Ornitz, D. M., 1985, In: Federation proceedings. 44, 5, p. No. 7923

  Research output: Contribution to journal › Article › peer-review

• Targeted fibrillar nanocarbon RNAi treatment of acute kidney injury

  Alidori, S., Akhavein, N., Thorek, D. L. J., Behling, K., Romin, Y., Queen, D., Beattie, B. J., Manova-Todorova, K., Bergkvist, M., Scheinberg, D. A. & McDevitt, M. R., Mar 23 2016, In: Science translational medicine. 8, 331, 331ra39.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  72 Scopus citations

• Targeted fluid minimization following initial resuscitation in septic shock a pilot study

  Chen, C. & Kollef, M. H., Dec 2015, In: CHEST. 148, 6, p. 1462-1469 8 p.

  Research output: Contribution to journal › Article › peer-review
  57 Scopus citations

• Targeted Gene Delivery by Tropism-Modified Adenoviral Vectors

  Douglas, J. T., Rogers, B. E., Rosenfeld, M. E., Michael, S. I., Feng, M. & Curiel, D. T., Nov 1996, In: Nature Biotechnology. 14, 11, p. 1574-1578 5 p.

  Research output: Contribution to journal › Article › peer-review
  313 Scopus citations

• Targeted gene delivery to Kaposi's sarcoma cells via the fibroblast growth factor receptor

  Goldman, C. K., Rogers, B. E., Douglas, J. T., Sosnowski, B. A., Ying, W., Siegal, G. P., Baird, A., Campain, J. A. & Curiel, D. T., 1997, In: Cancer research. 57, 8, p. 1447-1451 5 p.

  Research output: Contribution to journal › Article › peer-review

  23 Scopus citations

• Targeted gene disruption of matrix metalloproteinase-9 (gelatinase B) suppresses development of experimental abdominal aortic aneurysms

  Pyo, R., Lee, J. K., Shipley, J. M., Curci, J. A., Mao, D., Ziporin, S. J., Ennis, T. L., Shapiro, S. D., Senior, R. M. & Thompson, R. W., Jun 2000, In: Journal of Clinical Investigation. 105, 11, p. 1641-1649 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  711 Scopus citations

• Targeted gene expression in the zebrafish prechordal plate

  Inbal, A., Topczewski, J. & Solnica-Krezel, L., Dec 2006, In: Genesis. 44, 12, p. 584-588 5 p.

  Research output: Contribution to journal › Article › peer-review
  16 Scopus citations

• Targeted gene replacement demonstrates that myristoyl-CoA:protein N- myristoyltransferase is essential for viability of Cryptococcus neoformans

  Lodge, J. K., Jackson-Machelski, E., Toffaletti, D. L., Perfect, J. R. & Gordon, J. I., 1994, In: Proceedings of the National Academy of Sciences of the United States of America. 91, 25, p. 12008-12012 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  170 Scopus citations

• Targeted gene silencing of tumor necrosis factor: Attenuates the negative inotropic effects of lipopolysaccharide in isolated contracting cardiac myocytes

  Ramabadran, R. S., Chancey, A., Vallejo, J. G., Barger, P. M., Sivasubramanian, N. & Mann, D. L., 2008, In: Texas Heart Institute journal. 35, 1, p. 16-21 6 p.

  Research output: Contribution to journal › Article › peer-review

  2 Scopus citations

• Targeted gene therapy for ovarian cancer

  Rocconi, R. P., Numnum, T. M., Stoff-Khalili, M., Makhija, S., Alvarez, R. D. & Curiel, D. T., Dec 1 2005, In: Current gene therapy. 5, 6, p. 643-653 11 p.

  Research output: Contribution to journal › Review article › peer-review
  19 Scopus citations

• Targeted genetic and viral therapy for advanced head and neck cancers

  Huang, P. I., Chang, J. F., Kirn, D. H. & Liu, T. C., Jun 1 2009, In: Drug Discovery Today. 14, 11-12, p. 570-578 9 p.

  Research output: Contribution to journal › Review article › peer-review
  21 Scopus citations

• Targeted gene transfer to human hematopoietic progenitor cell lines through the c-kit receptor

  Schwarzenberger, P., Spence, S. E., Gooya, J. M., Michiel, D., Curiel, D. T., Ruscetti, F. W. & Keller, J. R., Jan 15 1996, In: Blood. 87, 2, p. 472-478 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  54 Scopus citations

• Targeted genome modification in mice using zinc-finger nucleases

  Carbery, I. D., Ji, D., Harrington, A., Brown, V., Weinstein, E. J., Liaw, L. & Cui, X., Oct 2010, In: Genetics. 186, 2, p. 451-459 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  225 Scopus citations

• Targeted glycoprotein enrichment and identification in stromal cell secretomes using azido sugar metabolic labeling

  Roper, S. M., Zemskova, M., Neely, B. A., Martin, A., Gao, P., Jones, E. E., Kraft, A. S. & Drake, R. R., Jun 2013, In: Proteomics - Clinical Applications. 7, 5-6, p. 367-371 5 p.

  Research output: Contribution to journal › Article › peer-review
  15 Scopus citations

• Targeted inhibition of cyclic AMP phosphodiesterase-4 promotes brain tumor regression

  Goldhoff, P., Warrington, N. M., Limbrick, D. D., Hope, A., Woerner, B. M., Jackson, E., Perry, A., Piwnica-Worms, D. & Rubin, J. B., Dec 1 2008, In: Clinical Cancer Research. 14, 23, p. 7717-7725 9 p.

  Research output: Contribution to journal › Article › peer-review
  107 Scopus citations

• Targeted inhibition of interferon-γ-dependent intercellular adhesion molecule-1 (ICAM-1) expression using dominant-negative Stat1

  Walter, M. J., Look, D. C., Tidwell, R. M., Roswit, W. T. & Holtzman, M. J., Nov 7 1997, In: Journal of Biological Chemistry. 272, 45, p. 28582-28589 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  83 Scopus citations

• Targeted inhibition of mammalian target of rapamycin signaling inhibits tumorigenesis of colorectal cancer

  Gulhati, P., Cai, Q., Li, J., Liu, J., Rychahou, P. G., Qiu, S., Lee, E. Y., Silva, S. R., Bowen, K. A., Gao, T. & Evers, B. M., Dec 1 2009, In: Clinical Cancer Research. 15, 23, p. 7207-7216 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  143 Scopus citations

• Targeted inhibition of Phospholipase C γ2 adaptor function blocks osteoclastogenesis and protects from pathological osteolysis

  Decker, C., Hesker, P., Zhang, K. & Faccio, R., Nov 22 2013, In: Journal of Biological Chemistry. 288, 47, p. 33634-33641 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  9 Scopus citations

• Targeted inhibition of the small GTPase protects against ischemia/reperfusion liver injury in mice

  Ozaki, M., Deshpande, S., Angkeow, P., Bellan, J., Lowenstein, C. J., Dinauer, M. C., Goldschmidt-Clermont, P., Suzuki, S. & Irani, K., 2001, In: Transplantation Proceedings. 33, 1-2, p. 863-864 2 p.

  Research output: Contribution to journal › Article › peer-review
  7 Scopus citations

• Targeted inhibition of thrombin attenuates murine neonatal necrotizing enterocolitis

  Namachivayam, K., MohanKumar, K., Shores, D. R., Jain, S. K., Fundora, J., Everett, A. D., He, L., Pan, H., Wickline, S. A. & Maheshwari, A., May 19 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 20, p. 10958-10969 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  14 Scopus citations

• Targeted inhibition of V(D)J recombination by a histone methyltransferase

  Osipovich, O., Milley, R., Meade, A., Tachibana, M., Shinkai, Y., Krangel, M. S. & Oltz, E. M., Mar 2004, In: Nature immunology. 5, 3, p. 309-316 8 p.

  Research output: Contribution to journal › Article › peer-review
  28 Scopus citations

• Targeted integration in rat and mouse embryos with zinc-finger nucleases

  Cui, X., Ji, D., Fisher, D. A., Wu, Y., Briner, D. M. & Weinstein, E. J., Jan 1 2011, In: Nature Biotechnology. 29, 1, p. 64-68 5 p.

  Research output: Contribution to journal › Article › peer-review
  270 Scopus citations

• Targeted interruption of the psaA and psaB genes encoding the reaction‐centre proteins of photosystem I in the filamentous cyanobacterium Anabaena variabilis ATCC 29413

  Nyhus, K. J., Thiel, T. & Pakrasi, H. B., Sep 1993, In: Molecular Microbiology. 9, 5, p. 979-988 10 p.

  Research output: Contribution to journal › Article › peer-review
  2 Scopus citations

• Targeted intestinal overexpression of the immediate early gene tis7 in transgenic mice increases triglyceride absorption and adiposity

  Wang, Y., Iordanov, H., Swietlicki, E. A., Wang, L., Fritsch, C., Coleman, T., Semenkovich, C. F., Levin, M. S. & Rubin, D. C., Oct 14 2005, In: Journal of Biological Chemistry. 280, 41, p. 34764-34775 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  20 Scopus citations

• Targeted in vivo knock-in of human alpha-1-antitrypsin cDNA using adenoviral delivery of CRISPR/Cas9

  Stephens, C. J., Kashentseva, E., Everett, W., Kaliberova, L. & Curiel, D. T., Apr 1 2018, In: Gene therapy. 25, 2, p. 139-156 18 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  34 Scopus citations

• Targeted knock-in mice expressing mutations of CD28 reveal an essential pathway for costimulation

  Dodson, L. F., Boomer, J. S., Deppong, C. M., Shah, D. D., Sim, J., Bricker, T. L., Russell, J. H. & Green, J. M., Jul 2009, In: Molecular and cellular biology. 29, 13, p. 3710-3721 12 p.

  Research output: Contribution to journal › Article › peer-review
  60 Scopus citations

• Targeted loss of proteoglycans results in changes of frequency-dependent viscoelastic behavior of the intact articular cartilage

  Tang, S. Y. & Alliston, T., Dec 1 2012, ASME 2012 Summer Bioengineering Conference, SBC 2012. p. 299-300 2 p. (ASME 2012 Summer Bioengineering Conference, SBC 2012).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

• Targeted magnetic resonance imaging contrast agents.

  Caruthers, S. D., Winter, P. M., Wickline, S. A. & Lanza, G. M., 2006, In: Methods in Molecular Medicine. 124, p. 387-400 14 p.

  Research output: Contribution to journal › Review article › peer-review

  39 Scopus citations

• Targeted Memory Reactivation During Sleep, But Not Wake, Enhances Sensorimotor Skill Performance: A Pilot Study

  Johnson, B. P., Scharf, S. M. & Westlake, K. P., Mar 4 2018, In: Journal of Motor Behavior. 50, 2, p. 202-209 8 p.

  Research output: Contribution to journal › Article › peer-review
  8 Scopus citations

• Targeted metabolomic profiling of low and high grade serous epithelial ovarian cancer tissues: a pilot study

  Garg, G., Yilmaz, A., Kumar, P., Turkoglu, O., Mutch, D. G., Powell, M. A., Rosen, B., Bahado-Singh, R. O. & Graham, S. F., Dec 1 2018, In: Metabolomics. 14, 12, 154.

  Research output: Contribution to journal › Article › peer-review
  13 Scopus citations