68Ga-Prostate-Specific Membrane Antigen PET/CT and 18F-FDG PET/CT of Primary Signet Ring Cell Breast Adenocarcinoma

Ashwin Singh Parihar, Bhagwant Rai Mittal, Apurva Sood, Rajender Kumar Basher, Gurpreet Singh

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

Primary signet ring cell adenocarcinoma of the breast is a rare neoplasm. Similar to other mucinous neoplasms, it has low FDG avidity and poor prognosis compared with the traditional ductal/lobular carcinomas. We present a case of a 40-year-old woman with signet ring cell adenocarcinoma and skeletal fluorosis showing higher uptake of 68Ga-prostate-specific membrane antigen in the primary lesion and the metastatic sites compared with 18F-FDG on PET/CT imaging. Additionally, diffuse increased prostate-specific membrane antigen uptake was noticed in the entire skeleton, likely due to skeletal fluorosis.

Original languageEnglish
Pages (from-to)e414-e416
JournalClinical nuclear medicine
Volume43
Issue number11
DOIs
StatePublished - Nov 1 2018

Keywords

  • F-FDG PET/CT
  • Ga-PSMA PET/CT
  • breast carcinoma
  • fluorosis
  • signet ring cell adenocarcinoma

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