TY - JOUR
T1 - 68Ga-Prostate-Specific Membrane Antigen PET/CT and 18F-FDG PET/CT of Primary Signet Ring Cell Breast Adenocarcinoma
AU - Parihar, Ashwin Singh
AU - Mittal, Bhagwant Rai
AU - Sood, Apurva
AU - Basher, Rajender Kumar
AU - Singh, Gurpreet
N1 - Publisher Copyright:
© Wolters Kluwer Health, Inc. All rights reserved.
PY - 2018/11/1
Y1 - 2018/11/1
N2 - Primary signet ring cell adenocarcinoma of the breast is a rare neoplasm. Similar to other mucinous neoplasms, it has low FDG avidity and poor prognosis compared with the traditional ductal/lobular carcinomas. We present a case of a 40-year-old woman with signet ring cell adenocarcinoma and skeletal fluorosis showing higher uptake of 68Ga-prostate-specific membrane antigen in the primary lesion and the metastatic sites compared with 18F-FDG on PET/CT imaging. Additionally, diffuse increased prostate-specific membrane antigen uptake was noticed in the entire skeleton, likely due to skeletal fluorosis.
AB - Primary signet ring cell adenocarcinoma of the breast is a rare neoplasm. Similar to other mucinous neoplasms, it has low FDG avidity and poor prognosis compared with the traditional ductal/lobular carcinomas. We present a case of a 40-year-old woman with signet ring cell adenocarcinoma and skeletal fluorosis showing higher uptake of 68Ga-prostate-specific membrane antigen in the primary lesion and the metastatic sites compared with 18F-FDG on PET/CT imaging. Additionally, diffuse increased prostate-specific membrane antigen uptake was noticed in the entire skeleton, likely due to skeletal fluorosis.
KW - F-FDG PET/CT
KW - Ga-PSMA PET/CT
KW - breast carcinoma
KW - fluorosis
KW - signet ring cell adenocarcinoma
UR - http://www.scopus.com/inward/record.url?scp=85054459734&partnerID=8YFLogxK
U2 - 10.1097/RLU.0000000000002265
DO - 10.1097/RLU.0000000000002265
M3 - Article
C2 - 30247208
AN - SCOPUS:85054459734
VL - 43
SP - e414-e416
JO - Clinical Nuclear Medicine
JF - Clinical Nuclear Medicine
SN - 0363-9762
IS - 11
ER -