6-acetylmorphine detected in the absence of morphine in pain management patients

Bridgit Crews, Charles Mikel, Sergey Latyshev, Robert West, Cameron West, Amadeo Pesce, Patrick Friel

Research output: Contribution to journalArticlepeer-review

15 Scopus citations

Abstract

Liquid chromatography tandem mass spectrometry was used to identify and confirm the presence of 6-acetylmorphine and morphine in 22,361 urines of pain management patients. Thirty urines tested positive for 6-acetylmorphine above a cutoff of 10 ng/mL. Twenty-three percent of the patients with urinary concentrations of 6-acetylmorphine above 10 ng/mL had urinary morphine concentrations below 300 ng/mL.

Original languageEnglish
Pages (from-to)749-752
Number of pages4
JournalTherapeutic Drug Monitoring
Volume31
Issue number6
DOIs
StatePublished - Dec 2009

Keywords

  • 6-Acetylmorphine
  • Cutoffs
  • Morphine
  • Pain patients
  • Urinary excretion

Fingerprint

Dive into the research topics of '6-acetylmorphine detected in the absence of morphine in pain management patients'. Together they form a unique fingerprint.

Cite this