5-HT2A Receptor Agonism Changes Neuronal Network Activity and Disrupts Neurovascular Coupling in Mice

Jonah Padawer-Curry; Joshua S. Siegel; Jordan G. McCall; Ginger E. Nicol; Adam Q. Bauer

5-HT2A Receptor Agonism Changes Neuronal Network Activity and Disrupts Neurovascular Coupling in Mice

Jonah Padawer-Curry, Joshua S. Siegel, Jordan G. McCall, Ginger E. Nicol, Adam Q. Bauer

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

Thy1-jRGECO1a mice were imaged under awake, resting-state conditions using wide-field optical imaging. Non-hallucinogenic 5-HT2a receptor agonism significantly reduced neuronal and hemodynamic bilateral functional connectivity, activity, and neurovascular coupling in a region- and frequency-band-specific manner.

Original language	English
Title of host publication	Optics and the Brain, BRAIN 2023
Publisher	Optical Society of America
ISBN (Electronic)	9781957171210
State	Published - 2023
Event	Optics and the Brain, BRAIN 2023 - Part of Optica Biophotonics Congress: Optics in the Life Sciences 2023 - Vancouver, Canada Duration: Apr 24 2023 → Apr 27 2023

Publication series

Name	Optics and the Brain, BRAIN 2023

Conference

Conference	Optics and the Brain, BRAIN 2023 - Part of Optica Biophotonics Congress: Optics in the Life Sciences 2023
Country/Territory	Canada
City	Vancouver
Period	04/24/23 → 04/27/23

Cite this

@inproceedings{9246f741b6e1408397755fe626504bfd,

title = "5-HT2A Receptor Agonism Changes Neuronal Network Activity and Disrupts Neurovascular Coupling in Mice",

abstract = "Thy1-jRGECO1a mice were imaged under awake, resting-state conditions using wide-field optical imaging. Non-hallucinogenic 5-HT2a receptor agonism significantly reduced neuronal and hemodynamic bilateral functional connectivity, activity, and neurovascular coupling in a region- and frequency-band-specific manner.",

author = "Jonah Padawer-Curry and Siegel, {Joshua S.} and McCall, {Jordan G.} and Nicol, {Ginger E.} and Bauer, {Adam Q.}",

note = "Publisher Copyright: {\textcopyright} 2023 The Author (s).; Optics and the Brain, BRAIN 2023 - Part of Optica Biophotonics Congress: Optics in the Life Sciences 2023 ; Conference date: 24-04-2023 Through 27-04-2023",

year = "2023",

language = "English",

series = "Optics and the Brain, BRAIN 2023",

publisher = "Optical Society of America",

booktitle = "Optics and the Brain, BRAIN 2023",

}

Padawer-Curry, J, Siegel, JS, McCall, JG , Nicol, GE & Bauer, AQ 2023, 5-HT2A Receptor Agonism Changes Neuronal Network Activity and Disrupts Neurovascular Coupling in Mice. in Optics and the Brain, BRAIN 2023., BTu2B.3, Optics and the Brain, BRAIN 2023, Optical Society of America, Optics and the Brain, BRAIN 2023 - Part of Optica Biophotonics Congress: Optics in the Life Sciences 2023, Vancouver, Canada, 04/24/23.

5-HT2A Receptor Agonism Changes Neuronal Network Activity and Disrupts Neurovascular Coupling in Mice. / Padawer-Curry, Jonah; Siegel, Joshua S.; McCall, Jordan G. et al.
Optics and the Brain, BRAIN 2023. Optical Society of America, 2023. BTu2B.3 (Optics and the Brain, BRAIN 2023).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - 5-HT2A Receptor Agonism Changes Neuronal Network Activity and Disrupts Neurovascular Coupling in Mice

AU - Padawer-Curry, Jonah

AU - Siegel, Joshua S.

AU - McCall, Jordan G.

AU - Nicol, Ginger E.

AU - Bauer, Adam Q.

PY - 2023

Y1 - 2023

N2 - Thy1-jRGECO1a mice were imaged under awake, resting-state conditions using wide-field optical imaging. Non-hallucinogenic 5-HT2a receptor agonism significantly reduced neuronal and hemodynamic bilateral functional connectivity, activity, and neurovascular coupling in a region- and frequency-band-specific manner.

AB - Thy1-jRGECO1a mice were imaged under awake, resting-state conditions using wide-field optical imaging. Non-hallucinogenic 5-HT2a receptor agonism significantly reduced neuronal and hemodynamic bilateral functional connectivity, activity, and neurovascular coupling in a region- and frequency-band-specific manner.

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M3 - Conference contribution

AN - SCOPUS:85191162520

T3 - Optics and the Brain, BRAIN 2023

BT - Optics and the Brain, BRAIN 2023

PB - Optical Society of America

T2 - Optics and the Brain, BRAIN 2023 - Part of Optica Biophotonics Congress: Optics in the Life Sciences 2023

Y2 - 24 April 2023 through 27 April 2023

ER -

5-HT2A Receptor Agonism Changes Neuronal Network Activity and Disrupts Neurovascular Coupling in Mice

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