3D visualization of the ovarian tissue scattering coefficient with swept-source optical coherence tomography

Yifeng Zeng, Bin Rao, Sreyankar Nandy, Ian Hagemann, Cary Siegel, Matthew Powell, Quing Zhu

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Abstract

It is important to provide timely information to surgeons on diagnosis of a suspicious ovarian tissue before excision to avoid unnecessary surgery, especially for young women. In this report, we introduce a new 3-D surface mapping technique to map ovarian tissue scattering properties by fitting the swept-source optical coherence tomography (SS-OCT) signals to a scattering model. We observed that lower scattering coefficients and heterogeneous spatial distribution were associated with malignant ovarian tissues, and higher scattering coefficients and homogeneous spatial distribution indicated benign ovarian tissues. The initial results suggest that the 3-D scattering map has potential to be an effective tool to characterize normal and malignant ovarian tissues.

Original languageEnglish
Title of host publicationOptical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXII
EditorsValery V. Tuchin, Valery V. Tuchin, James G. Fujimoto, Joseph A. Izatt
PublisherSPIE
ISBN (Electronic)9781510614512
DOIs
StatePublished - Jan 1 2018
EventOptical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXII 2018 - San Francisco, United States
Duration: Jan 29 2018Jan 31 2018

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume10483
ISSN (Print)1605-7422

Conference

ConferenceOptical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXII 2018
CountryUnited States
CitySan Francisco
Period01/29/1801/31/18

Keywords

  • collagen
  • ovarian tissue
  • scattering coefficient
  • swept-source optical coherence tomography

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    Zeng, Y., Rao, B., Nandy, S., Hagemann, I., Siegel, C., Powell, M., & Zhu, Q. (2018). 3D visualization of the ovarian tissue scattering coefficient with swept-source optical coherence tomography. In V. V. Tuchin, V. V. Tuchin, J. G. Fujimoto, & J. A. Izatt (Eds.), Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXII [1048338] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 10483). SPIE. https://doi.org/10.1117/12.2291718