A 3D printable and highly stretchable tough hydrogel is developed by combining poly(ethylene glycol) and sodium alginate, which synergize to form a hydrogel tougher than natural cartilage. Encapsulated cells maintain high viability over a 7 d culture period and are highly deformed together with the hydrogel. By adding biocompatible nanoclay, the tough hydrogel is 3D printed in various shapes without requiring support material.

Original languageEnglish
Pages (from-to)4035-4040
Number of pages6
JournalAdvanced Materials
Issue number27
StatePublished - Jul 1 2015


  • 3D printing
  • cellularized structure
  • nanoclay
  • poly (ethylene glycol)-alginate
  • tough hydrogel


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