3D Printing of Highly Stretchable and Tough Hydrogels into Complex, Cellularized Structures

Sungmin Hong, Dalton Sycks, Hon Fai Chan, Shaoting Lin, Gabriel P. Lopez, Farshid Guilak, Kam W. Leong, Xuanhe Zhao

Research output: Contribution to journalArticlepeer-review

583 Scopus citations

Abstract

A 3D printable and highly stretchable tough hydrogel is developed by combining poly(ethylene glycol) and sodium alginate, which synergize to form a hydrogel tougher than natural cartilage. Encapsulated cells maintain high viability over a 7 d culture period and are highly deformed together with the hydrogel. By adding biocompatible nanoclay, the tough hydrogel is 3D printed in various shapes without requiring support material.

Original languageEnglish
Pages (from-to)4035-4040
Number of pages6
JournalAdvanced Materials
Volume27
Issue number27
DOIs
StatePublished - Jul 1 2015

Keywords

  • 3D printing
  • cellularized structure
  • nanoclay
  • poly (ethylene glycol)-alginate
  • tough hydrogel

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