3D Printing of Highly Stretchable and Tough Hydrogels into Complex, Cellularized Structures

Sungmin Hong; Dalton Sycks; Hon Fai Chan; Shaoting Lin; Gabriel P. Lopez; Farshid Guilak; Kam W. Leong; Xuanhe Zhao

doi:10.1002/adma.201501099

3D Printing of Highly Stretchable and Tough Hydrogels into Complex, Cellularized Structures

Sungmin Hong, Dalton Sycks, Hon Fai Chan, Shaoting Lin, Gabriel P. Lopez, Farshid Guilak, Kam W. Leong, Xuanhe Zhao

Research output: Contribution to journal › Article › peer-review

662 Scopus citations

Abstract

A 3D printable and highly stretchable tough hydrogel is developed by combining poly(ethylene glycol) and sodium alginate, which synergize to form a hydrogel tougher than natural cartilage. Encapsulated cells maintain high viability over a 7 d culture period and are highly deformed together with the hydrogel. By adding biocompatible nanoclay, the tough hydrogel is 3D printed in various shapes without requiring support material.

Original language	English
Pages (from-to)	4035-4040
Number of pages	6
Journal	Advanced Materials
Volume	27
Issue number	27
DOIs	https://doi.org/10.1002/adma.201501099
State	Published - Jul 1 2015

Keywords

3D printing
cellularized structure
nanoclay
poly (ethylene glycol)-alginate
tough hydrogel

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10.1002/adma.201501099

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abstract = "A 3D printable and highly stretchable tough hydrogel is developed by combining poly(ethylene glycol) and sodium alginate, which synergize to form a hydrogel tougher than natural cartilage. Encapsulated cells maintain high viability over a 7 d culture period and are highly deformed together with the hydrogel. By adding biocompatible nanoclay, the tough hydrogel is 3D printed in various shapes without requiring support material.",

keywords = "3D printing, cellularized structure, nanoclay, poly (ethylene glycol)-alginate, tough hydrogel",

author = "Sungmin Hong and Dalton Sycks and Chan, {Hon Fai} and Shaoting Lin and Lopez, {Gabriel P.} and Farshid Guilak and Leong, {Kam W.} and Xuanhe Zhao",

note = "Publisher Copyright: {\textcopyright} 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.",

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AU - Hong, Sungmin

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AU - Chan, Hon Fai

AU - Lin, Shaoting

AU - Lopez, Gabriel P.

AU - Guilak, Farshid

AU - Leong, Kam W.

AU - Zhao, Xuanhe

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KW - 3D printing

KW - cellularized structure

KW - nanoclay

KW - poly (ethylene glycol)-alginate

KW - tough hydrogel

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3D Printing of Highly Stretchable and Tough Hydrogels into Complex, Cellularized Structures

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Keywords

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