TY - GEN
T1 - 3 State neurons for contextual processing
AU - Kepecs, Adam
AU - Ragliavacliari, Sridhar
PY - 2002
Y1 - 2002
N2 - Neurons receive excitatory inputs via both fast AMPA and slow NMD A type receptors. We find that neurons receiving input via NMDA receptors can have two stable membrane states which are input dependent. Action potentials can only be initiated from the higher voltage state. Similar observations have been made in several brain areas which might be explained by our model. The in-teractions between the two kinds of inputs lead us to suggest that some neurons may operate in 3 states: disabled, enabled and firing. Such enabled, but non-firing modes can be used to introduce context-dependent processing in neural networks. We provide a simple example and discuss possible implications for neuronal processing and response variability.
AB - Neurons receive excitatory inputs via both fast AMPA and slow NMD A type receptors. We find that neurons receiving input via NMDA receptors can have two stable membrane states which are input dependent. Action potentials can only be initiated from the higher voltage state. Similar observations have been made in several brain areas which might be explained by our model. The in-teractions between the two kinds of inputs lead us to suggest that some neurons may operate in 3 states: disabled, enabled and firing. Such enabled, but non-firing modes can be used to introduce context-dependent processing in neural networks. We provide a simple example and discuss possible implications for neuronal processing and response variability.
UR - http://www.scopus.com/inward/record.url?scp=84898958565&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:84898958565
SN - 0262042088
SN - 9780262042086
T3 - Advances in Neural Information Processing Systems
BT - Advances in Neural Information Processing Systems 14 - Proceedings of the 2001 Conference, NIPS 2001
PB - Neural information processing systems foundation
T2 - 15th Annual Neural Information Processing Systems Conference, NIPS 2001
Y2 - 3 December 2001 through 8 December 2001
ER -