TY - JOUR
T1 - 2006 Consensus guidelines for the management of women with cervical intraepithelial neoplasia or adenocarcinoma in situ
AU - Wright, Thomas C.
AU - Massad, L. Stewart
AU - Dunton, Charles J.
AU - Spitzer, Mark
AU - Wilkinson, Edward J.
AU - Solomon, Diane
N1 - Funding Information:
We would like to thank all of the participants and formal observers to the 2006 Consensus Conference who worked so hard to develop the guidelines. Their names and organizations are available ( www.asccp.org ). We would like to thank Ms Kathy Poole for administrative support during the development of the guidelines and Dr Anna Barbara Moscicki, who chaired the adolescent working group. These guidelines were developed with funding from the American Society for Colposcopy and Cervical Pathology and the National Cancer Institute. Its contents are solely the responsibility of the authors and the American Society for Colposcopy and Cervical Pathology and do not necessarily represent the official views of the National Cancer Institute.
PY - 2007/10
Y1 - 2007/10
N2 - OBJECTIVE. To provide updated consensus guidelines for the management of women with cervical intraepithelial neoplasia (CIN) or adenocarcinoma in situ (AIS). PARTICIPANTS. A group of 146 experts including representatives from 29 professional organizations, federal agencies, and national and international health organizations met on September 18-19, 2006, in Bethesda, MD, to develop the guidelines. MAJOR CHANGES IN THE GUIDELINES. The management of women with CIN grade 1 (CIN 1) has been modified significantly. In the earlier guidelines, management depended on whether the colposcopic examination was satisfactory and treatment using ablative or excisional methods was acceptable for women with CIN 1. In the new guidelines, cytological follow-up is the only recommended management option, regardless of whether the colposcopic examination is satisfactory, for women with CIN 1 who have a low-grade referral cervical cytology. Treatment of CIN 1 is particularly discouraged in adolescents. The basic management of women in the general population with CIN 2,3 underwent only minor modifications, but options for the conservative management of adolescents with CIN 2,3 have been expanded. Moreover, management recommendations for women with biopsy-confirmed AIS are now included. CONCLUSION. Updated evidenced-based guidelines have been developed for the management of women with CIN or AIS. These guidelines reflect recent changes in our understanding of human papillomavirus-associated diseases of the cervix and the potential impact of treatment on future pregnancies.
AB - OBJECTIVE. To provide updated consensus guidelines for the management of women with cervical intraepithelial neoplasia (CIN) or adenocarcinoma in situ (AIS). PARTICIPANTS. A group of 146 experts including representatives from 29 professional organizations, federal agencies, and national and international health organizations met on September 18-19, 2006, in Bethesda, MD, to develop the guidelines. MAJOR CHANGES IN THE GUIDELINES. The management of women with CIN grade 1 (CIN 1) has been modified significantly. In the earlier guidelines, management depended on whether the colposcopic examination was satisfactory and treatment using ablative or excisional methods was acceptable for women with CIN 1. In the new guidelines, cytological follow-up is the only recommended management option, regardless of whether the colposcopic examination is satisfactory, for women with CIN 1 who have a low-grade referral cervical cytology. Treatment of CIN 1 is particularly discouraged in adolescents. The basic management of women in the general population with CIN 2,3 underwent only minor modifications, but options for the conservative management of adolescents with CIN 2,3 have been expanded. Moreover, management recommendations for women with biopsy-confirmed AIS are now included. CONCLUSION. Updated evidenced-based guidelines have been developed for the management of women with CIN or AIS. These guidelines reflect recent changes in our understanding of human papillomavirus-associated diseases of the cervix and the potential impact of treatment on future pregnancies.
KW - Adenocarcinomas in situ of the cervix
KW - Cervical intraepithelial neoplasia
KW - Cryotherapy
KW - Loop electrosurgical excision procedure
KW - Treatment
UR - http://www.scopus.com/inward/record.url?scp=34948815559&partnerID=8YFLogxK
U2 - 10.1097/LGT.0b013e318159408b
DO - 10.1097/LGT.0b013e318159408b
M3 - Article
C2 - 17917567
AN - SCOPUS:34948815559
SN - 1089-2591
VL - 11
SP - 223
EP - 239
JO - Journal of lower genital tract disease
JF - Journal of lower genital tract disease
IS - 4
ER -