2006 consensus guidelines for the management of women with abnormal cervical cancer screening tests

Thomas C. Wright, L. Stewart Massad, Charles J. Dunton, Mark Spitzer, Edward J. Wilkinson, Diane Solomon

Research output: Contribution to journalReview articlepeer-review

655 Scopus citations

Abstract

A group of 146 experts representing 29 organizations and professional societies met September 18-19, 2006, in Bethesda, MD, to develop revised evidence-based, consensus guidelines for managing women with abnormal cervical cancer screening tests. Recommendations for managing atypical squamous cells of undetermined significance and low-grade squamous intraepithelial lesion (LSIL) are essentially unchanged. Changes were made for managing these conditions in adolescents for whom cytological follow-up for 2 years was approved. Recommendations for managing high-grade squamous intraepithelial lesion (HSIL) and atypical glandular cells (AGC) also underwent only minor modifications. More emphasis is placed on immediate screen-and-treat approaches for HSIL. Human papillomavirus (HPV) testing is incorporated into the management of AGC after their initial evaluation with colposcopy and endometrial sampling. The 2004 Interim Guidance for HPV testing as an adjunct to cervical cytology for screening in women 30 years of age and older was formally adopted with only very minor modifications.

Original languageEnglish
Pages (from-to)346-355
Number of pages10
JournalAmerican journal of obstetrics and gynecology
Volume197
Issue number4
DOIs
StatePublished - Oct 1 2007

Keywords

  • atypical squamous cells of undetermined significance
  • cervical cancer screening
  • cervical cytology
  • high-grade squamous intraepithelial lesion
  • human papillomavirus testing
  • low-grade squamous intraepithelial lesion

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