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14-3-3 Proteins block apoptosis and differentially regulate MAPK cascades
Heming Xing
, Shaosong Zhang
,
Carla Weinheimer
,
Attila Kovacs
, Anthony J. Muslin
Division of Cardiology
Institute of Clinical and Translational Sciences (ICTS)
Center for Cardiovascular Research
Research output
:
Contribution to journal
›
Article
›
peer-review
260
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Scopus citations
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Keyphrases
Apoptosis
100%
14-3-3 Protein
100%
Protein Blocks
100%
MAPK Cascade
100%
P38 Mitogen-activated Protein Kinase (p38 MAPK)
66%
Mutant Forms
66%
JNK1
66%
Family Members
33%
Targeted Expression
33%
Fibroblasts
33%
Binding Protein
33%
Cultured Cells
33%
Signal Transduction
33%
SB202190
33%
Cardiomyocyte Apoptosis
33%
Dilated Cardiomyopathy
33%
Cardiac Tissue
33%
Pressure Overload
33%
Cultured Fibroblasts
33%
Increased Mortality
33%
Primary Function
33%
ERK MAPK
33%
Double mutant
33%
Transgenic Animals
33%
Dominant-negative mutant
33%
MAPK Inhibitors
33%
MAPK Activation
33%
UV-C Irradiation
33%
Phosphoserine
33%
Checkpoint Control
33%
Biochemistry, Genetics and Molecular Biology
Mitogen-Activated Protein Kinase
100%
14-3-3 Protein
100%
Programmed Cell Death
100%
P38 Mitogen-Activated Protein Kinases
75%
Fibroblast
50%
Signal Transduction
25%
Transfection
25%
Binding Protein
25%
Cardiac Muscle Cell
25%
Transgenic Animal
25%
Phosphoserine
25%
Neuroscience
Mitogen-Activated Protein Kinase
100%
14-3-3 Protein
100%
Programmed Cell Death
100%
P38 Mitogen-Activated Protein Kinases
75%
Fibroblast
50%
Protein Binding
25%
Dilated Cardiomyopathy
25%
Transfection
25%
Phosphoserine
25%
Signal Transduction
25%