Abstract
The Manα1,3(Xylβ1,2)Manα structural motif is common to both capsular polysaccharides of Cryptococcus neoformans and to cryptococcal glycosphingolipids. Comparative analysis of glycosphingolipid structural profiles in wild-type and mutant strains showed that the Xylβ1,2- transferase (Cxt1p) that participates in capsular polysaccharide biosynthesis is also the sole transferase responsible for adding xylose to C. neoformans glycosphingolipids.
Original language | English |
---|---|
Pages (from-to) | 1611-1615 |
Number of pages | 5 |
Journal | Eukaryotic Cell |
Volume | 7 |
Issue number | 9 |
DOIs | |
State | Published - Sep 2008 |