Abstract
Norepinephrine increases the concentration of adenosine 3′,5′-monophosphate (cyclic AMP) in an incubated suspension of brain microvessels. This response can be matched by other drugs that stimulate the β receptors, but the α-adrenergic agonist phenylephrine is without effect; β-adrenergic blockade abolishes the response while αa -adrenergic blockade produces no change. The data support the contention that cerebral capillary function is subject to adrenergic neural control.
Original language | English |
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Pages (from-to) | 330-332 |
Number of pages | 3 |
Journal | Science |
Volume | 204 |
Issue number | 4390 |
DOIs | |
State | Published - 1979 |