α1-noradrenergic receptor blockade decreases nuclear estrogen receptor binding in guinea pig hypothalamus and preoptic area

Ann S. Clark, Bruce Nock, Harvey H. Feder, Edward J. Roy

Research output: Contribution to journalArticlepeer-review

38 Scopus citations

Abstract

Prazosin, a putative α1-noradrenergic antagonist, reduced nuclear estrogen receptor levels in the hypothalamus and preoptic area of the estrogen-primed guinea pig. Noradrenergic transmission may alter steroid-dependent processes and neuroendocrine function through actions on steroid-concentrating cells.

Original languageEnglish
Pages (from-to)197-199
Number of pages3
JournalBrain Research
Volume330
Issue number1
DOIs
StatePublished - Mar 18 1985
Externally publishedYes

Keywords

  • estrogen receptors
  • norepinephrine
  • progestin receptors

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