α-Lipoic acid prevents lipotoxic cardiomyopathy in acyl CoA-synthase transgenic mice

Keyphrases

• Transgenic Mice 100%
• Acyl-CoA 100%
• CoA Synthase 100%
• Lipotoxic Cardiomyopathy 100%
• Lipoic Acid 100%
• Lipotoxicity 40%
• Leptin 40%
• AMP-activated Protein Kinase 40%
• Overexpression 20%
• Apoptosis 20%
• Food Intake 20%
• Myofiber 20%
• Echocardiogram 20%
• 4-fold 20%
• Energy Expenditure 20%
• Cardiomyocytes 20%
• Mouse Heart 20%
• Sterol Regulatory Element-binding protein-1c (SREBP-1c) 20%
• Dilated Cardiomyopathy 20%
• Peroxisome Proliferator-activated Receptor 20%
• Microscopy 20%
• Disorganization 20%
• Systolic Function 20%
• Hyperleptinemia 20%
• Interstitial Fibrosis 20%
• Triacylglycerol 20%
• Activation Energy 20%
• Food Restriction 20%
• Cardiac Lipotoxicity 20%
• Heart Size 20%

Pharmacology, Toxicology and Pharmaceutical Science

• Transgenic Mouse 100%
• Synthetase 100%
• Myocardial Disease 100%
• Acyl-CoA 100%
• Lipoic Acid 100%
• Lipotoxicity 60%
• Hydroxymethylglutaryl Coenzyme A Reductase Kinase 40%
• Leptin 40%
• Triacylglycerol 20%
• Peroxisome Proliferator Activated Receptor 20%
• Fibrosing Alveolitis 20%
• Congestive Cardiomyopathy 20%
• Hyperleptinemia 20%
• Sterol Regulatory Element Binding Protein 1c 20%
• Messenger RNA 20%
• Disorientation 20%