If you made any changes in Pure these will be visible here soon.

Personal profile

Research interests

We are interested in studying molecular and cellular mechanisms of itch. Chronic itch or pruritis is a major skin problem, which may result from the disorders of the skin, immune function as well as internal metabolisms. The majority of chronic pruritus is intractable and resistant to conventional anti-histamine therapy. The underlying mechanism of various pruritus is not understood. We are interested in identifying novel itch receptors, signaling molecules and neural circuits, and are using multi-disciplinary approaches including molecular, cellular, biochemical, genetic and electrophysiological approaches to understand how itch is transmitted, its relationship with pain, the skin and immune systems. We are working to identify novel compounds which can block the itch pathway, and developing chronic itch models which mimic different aspects of human pruritus. Once novel anti-itch compounds identified, we hope to bring them into novel anti-pruritus therapeutics.

Available to Mentor:

  • PhD/MSTP Students


Dive into the research topics where Zhoufeng Chen is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
  • 1 Similar Profiles


Recent external collaboration on country/territory level. Dive into details by clicking on the dots or