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Yidan Sun

Assistant Professor of Genetics

 https://orcid.org/0000-0003-4019-8077

    Willing to Mentor

    Available to Mentor:

    PhD/MSTP Students

    • 9
      Citations
    20232025

    Research activity per year

    Personal profile

    Research interests

    The Sun Lab is dedicated to understanding the molecular mysteries behind neurodegenerative diseases such as Alzheimer’s, Parkinson’s, ALS and other brain disorders using Multi-omics and AI techniques. Our research focuses on exploring how genetic and epigenetic factors—like gene transcription, alternative splicing, chromatin modifications, and the 3D organization of the genome—affect diseases.

    Available to Mentor:

    • PhD/MSTP Students

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    • Alternative promoter usage during organ development

      Tan, J. & Sun, Y., Mar 28 2025, In: PLoS genetics. 21, 3 March, e1011635.

      Research output: Contribution to journal › Article › peer-review

      Open Access

    • MOF-mediated PRDX1 acetylation regulates inflammatory macrophage activation

      Chen, H. R., Sun, Y., Mittler, G., Rumpf, T., Shvedunova, M., Grosschedl, R. & Akhtar, A., Sep 24 2024, In: Cell Reports. 43, 9, 114682.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      1 Scopus citations

    • MSL2 ensures biallelic gene expression in mammals

      Sun, Y., Wiese, M., Hmadi, R., Karayol, R., Seyfferth, J., Martinez Greene, J. A., Erdogdu, N. U., Deboutte, W., Arrigoni, L., Holz, H., Renschler, G., Hirsch, N., Foertsch, A., Basilicata, M. F., Stehle, T., Shvedunova, M., Bella, C., Pessoa Rodrigues, C., Schwalb, B. & Cramer, P. & 2 others, Manke, T. & Akhtar, A., Dec 7 2023, In: Nature. 624, 7990, p. 173-181 9 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      6 Scopus citations

    • The NSL complex is required for piRNA production from telomeric clusters

      Iyer, S. S., Sun, Y., Seyfferth, J., Manjunath, V., Samata, M., Alexiadis, A., Kulkarni, T., Gutierrez, N., Georgiev, P., Shvedunova, M. & Akhtar, A., Sep 2023, In: Life Science Alliance. 9, e202302194.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      2 Scopus citations