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Yang Li

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Yang Li

Assistant Professor of Neurological Surgery, Assistant Professor of Genetics

 https://orcid.org/0000-0001-6997-6018

    Willing to Mentor

    Available to Mentor:

    PhD Students, Postdocs, Residents and Fellows

    • 9997
      Citations
    20122026

    Research activity per year

    Personal profile

    Research interests

    Our research interests include developing innovative computational tools/methods and utilizing single-cell (epi)genomic techniques to gain a comprehensive understanding of gene regulation in mammalian models and human diseases, particularly in brain tumors and neuropsychiatric disorders. 

    Available to Mentor:

    • PhD Students
    • Postdocs
    • Residents and Fellows

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    Collaborations and top research areas from the last five years

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    • Trimodal single-cell profiling of transcriptome, epigenome and 3D genome in complex tissues with scHiCAR

      Wei, X., Xu, Y., Yang, D., Kim, K., Yi, L., Luo, W., Lin, X., Xiang, Y., Williams, A. B., Wang, X., Srivas, S., Tan, C., Zhang, K., Li, W., Li, Y. E., Yue, F., Huang, Z. J., Jung, I. & Diao, Y., 2026, (Accepted/In press) In: Nature Biotechnology.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      2   Link opens in a new tab Scopus citations

    • Author Correction: Conserved and divergent gene regulatory programs of the mammalian neocortex (Nature, (2023), 624, 7991, (390-402), 10.1038/s41586-023-06819-6)

      Zemke, N. R., Armand, E. J., Wang, W., Lee, S., Zhou, J., Li, Y. E., Liu, H., Tian, W., Nery, J. R., Castanon, R. G., Bartlett, A., Osteen, J. K., Li, D., Zhuo, X., Xu, V., Chang, L., Dong, K., Indralingam, H. S., Rink, J. A. & Xie, Y. & 13 others, Miller, M., Krienen, F. M., Zhang, Q., Taskin, N., Ting, J., Feng, G., McCarroll, S. A., Callaway, E. M., Wang, T., Lein, E. S., Behrens, M. M., Ecker, J. R. & Ren, B., Jan 25 2024, In: Nature. 625, 7996, p. E26

      Research output: Contribution to journal › Comment/debate

      Open Access

    • A comparative atlas of single-cell chromatin accessibility in the human brain

      Li, Y. E., Preissl, S., Miller, M., Johnson, N. D., Wang, Z., Jiao, H., Zhu, C., Wang, Z., Xie, Y., Poirion, O., Kern, C., Pinto-Duarte, A., Tian, W., Siletti, K., Emerson, N., Osteen, J., Lucero, J., Lin, L., Yang, Q. & Zhu, Q. & 19 others, Zemke, N., Espinoza, S., Yanny, A. M., Nyhus, J., Dee, N., Casper, T., Shapovalova, N., Hirschstein, D., Hodge, R. D., Linnarsson, S., Bakken, T., Levi, B., Keene, C. D., Shang, J., Lein, E., Wang, A., Behrens, M. M., Ecker, J. R. & Ren, B., Oct 13 2023, In: Science. 382, 6667, adf7044.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      96   Link opens in a new tab Scopus citations

    • A deep population reference panel of tandem repeat variation

      Ziaei Jam, H., Li, Y., DeVito, R., Mousavi, N., Ma, N., Lujumba, I., Adam, Y., Maksimov, M., Huang, B., Dolzhenko, E., Qiu, Y., Kakembo, F. E., Joseph, H., Onyido, B., Adeyemi, J., Bakhtiari, M., Park, J., Javadzadeh, S., Jjingo, D. & Adebiyi, E. & 2 others, Bafna, V. & Gymrek, M., Dec 2023, In: Nature communications. 14, 1, 6711.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      45   Link opens in a new tab Scopus citations

    • A guide to the BRAIN Initiative Cell Census Network data ecosystem

      Hawrylycz, M., Martone, M. E., Ascoli, G. A., Bjaalie, J. G., Dong, H. W., Ghosh, S. S., Gillis, J., Hertzano, R., Haynor, D. R., Hof, P. R., Kim, Y., Lein, E., Liu, Y., Miller, J. A., Mitra, P. P., Mukamel, E., Ng, L., Osumi-Sutherland, D., Peng, H. & Ray, P. L. & 83 others, Sanchez, R., Regev, A., Ropelewski, A., Scheuermann, R. H., Tan, S. Z. K., Thompson, C. L., Tickle, T., Tilgner, H., Varghese, M., Wester, B., White, O., Zeng, H., Aevermann, B., Allemang, D., Ament, S., Athey, T. L., Baker, C., Baker, K. S., Baker, P. M., Bandrowski, A., Banerjee, S., Bishwakarma, P., Carr, A., Chen, M., Choudhury, R., Cool, J., Creasy, H., D'Orazi, F., Degatano, K., Dichter, B., Ding, S. L., Dolbeare, T., Ecker, J. R., Fang, R., Fillion-Robin, J. C., Fliss, T. P., Gee, J., Gillespie, T., Gouwens, N., Zhang, G. Q., Halchenko, Y. O., Harris, N. L., Herb, B. R., Hintiryan, H., Hood, G., Horvath, S., Huo, B., Jarecka, D., Jiang, S., Khajouei, F., Kiernan, E. A., Kir, H., Kruse, L., Lee, C., Lelieveldt, B., Li, Y., Liu, H., Liu, L., Markuhar, A., Mathews, J., Mathews, K. L., Mezias, C., Miller, M. I., Mollenkopf, T., Mufti, S., Mungall, C. J., Orvis, J., Puchades, M. A., Qu, L., Receveur, J. P., Ren, B., Sjoquist, N., Staats, Tward, D., van Velthoven, C. T. J., Wang, Q., Xie, F., Xu, H., Yao, Z., Yun, Z., Zhang, Y. R., Zheng, W. J. & Zingg, B., Jun 2023, In: PLoS biology. 21, 6 June, e3002133.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      28   Link opens in a new tab Scopus citations
    View all 47 Research outputs