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Dysregulated lactate metabolism synergizes with ALS genetic risk factors to accelerate motor decline
Tendulkar, S., Wu, T., Strickland, A., Hackett, A. R., Sato-Yamada, Y., Mao, X., Sasaki, Y., Milbrandt, J., Bloom, A. J. & DiAntonio, A., Apr 2026, In: PloS one. 21, 4 April, e0347135.Research output: Contribution to journal › Article › peer-review
Open Access -
Constitutively active SARM1 variants that induce neuropathy are enriched in ALS patients
Bloom, A. J., Mao, X., Strickland, A., Sasaki, Y., Milbrandt, J. & DiAntonio, A., Dec 2022, In: Molecular neurodegeneration. 17, 1, 1.Research output: Contribution to journal › Article › peer-review
Open Access64 Link opens in a new tab Scopus citations -
Distinct developmental and degenerative functions of SARM1 require NAD+ hydrolase activity
Brace, E. J., Essuman, K., Mao, X., Palucki, J., Sasaki, Y., Milbrandt, J. & DiAntonio, A., Jun 23 2022, In: PLoS genetics. 18, 6, e1010246.Research output: Contribution to journal › Article › peer-review
Open Access12 Link opens in a new tab Scopus citations -
Structural basis of SARM1 activation, substrate recognition, and inhibition by small molecules
Shi, Y., Kerry, P. S., Nanson, J. D., Bosanac, T., Sasaki, Y., Krauss, R., Saikot, F. K., Adams, S. E., Mosaiab, T., Masic, V., Mao, X., Rose, F., Vasquez, E., Furrer, M., Cunnea, K., Brearley, A., Gu, W., Luo, Z., Brillault, L. & Landsberg, M. J. & 5 others, , May 5 2022, In: Molecular cell. 82, 9, p. 1643-1659.e10Research output: Contribution to journal › Article › peer-review
Open Access104 Link opens in a new tab Scopus citations -
Multiple domain interfaces mediate SARM1 autoinhibition
Shen, C., Vohra, M., Zhang, P., Mao, X., Figley, M. D., Zhu, J., Sasaki, Y., Wu, H., DiAntonio, A. & Milbrandt, J., Jan 26 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 4, e2023151118.Research output: Contribution to journal › Article › peer-review
Open Access49 Link opens in a new tab Scopus citations