William Hawkins

Research output

Research output per year 1999 2009 2011 2012 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023

• 182 Article
• 14 Review article
• 13 Comment/debate
• 6 Chapter
• 4 More
  • 2 Letter
  • 1 Editorial
  • 1 Short survey

Research output per year

Research output per year

Search results

• 2022

  Enhanced recovery pathway after open pancreaticoduodenectomy reduces postoperative length of hospital stay without reducing composite length of stay

  Takchi, R., Cos, H., Williams, G. A., Woolsey, C., Hammill, C., Fields, R. C., Strasberg, S. M., Hawkins, W. G. & Sanford, D. E., Jan 2022, In: HPB. 24, 1, p. 65-71 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Pancreaticoduodenectomy 100%
  • Length of Stay 64%
  • Propensity Score 22%
  • Ambulatory Surgical Procedures 13%
  • Matched-Pair Analysis 9%

• Improved outcomes with minimally invasive pancreaticoduodenectomy in patients with dilated pancreatic ducts: a prospective study

  Cos, H., LeCompte, M. T., Srinivasa, S., Zarate Rodriguez, J., Woolsey, C. A., Williams, G., Patel, S., Khan, A., Fields, R. C., Majella Doyle, M. B., Chapman, W. C., Strasberg, S. M., Hawkins, W. G., Hammill, C. W. & Sanford, D. E., May 2022, In: Surgical endoscopy. 36, 5, p. 3100-3109 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Pancreaticoduodenectomy 100%
  • Pancreatic Ducts 96%
  • Prospective Studies 53%
  • Propensity Score 17%
  • Perioperative Period 4%
  4 Scopus citations

• Increased Morbidity and Mortality After Hepatectomy for Colorectal Liver Metastases in Frail Patients is Largely Driven by Worse Outcomes After Minor Hepatectomy: It’s Not “Just a Wedge”

  Leigh, N., Williams, G. A., Strasberg, S., Fields, R. C., Hawkins, W. G., Hammill, C. W. & Sanford, D. E., Sep 2022, In: Annals of Surgical Oncology. 29, 9, p. 5476-5485 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Hepatectomy 100%
  • Frailty 62%
  • Neoplasm Metastasis 57%
  • Morbidity 55%
  • Liver 48%

• Malic Enzyme 1 Absence in Synovial Sarcoma Shifts Antioxidant System Dependence and Increases Sensitivity to Ferroptosis Induction with ACXT-3102

  Brashears, C. B., Prudner, B. C., Rathore, R., Caldwell, K. E., Dehner, C. A., Buchanan, J. L., Lange, S. E. S., Poulin, N., Sehn, J. K., Roszik, J., Spitzer, D., Jones, K. B., O’Keefe, R., Nielsen, T. O., Taylor, E. B., Held, J. M., Hawkins, W. & Van Tine, B. A., Aug 15 2022, In: Clinical Cancer Research. 28, 16, p. 3573-3589 17 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • malate dehydrogenase (decarboxylating) 100%
  • Ferroptosis 82%
  • Synovial Sarcoma 70%
  • Antioxidants 38%
  • Oxidation-Reduction 15%
  8 Scopus citations

• MITI minimum information guidelines for highly multiplexed tissue images

  Human Tumor Atlas Network, Ademuyiwa, F. O., Aft, R., Bayguinov, P., Cao, S., Caravan, W., Chasnoff, S., Chatterjee, D., Chen, F., Chen, S., Chheda, M. G., Colditz, G. A., Zhou, D. C., Davies, S. R., Denardo, D., Ding, L., DiPersio, J., Eberlein, T. J., Fields, R. C., Fitzpatrick, J., & 28 othersFulton, B., Gillanders, W. E., Hawkins, W. G., Hsieh, J. J., Iglesia, M. D., Jayasinghe, R. G., Ju, T., Kim, A. H., Krishnamoorthy, P., Li, Y., Liang, W. W., Lim, K. H., Liu, R., Ma, C., Maher, C., Mashl, J., McMichael, J., Mudd, J., Deen, N. N. A., Oh, S. T., Patti, G. J., Puram, S. V., Shoghi, K. I., Song, S. K., Veis, D. J., Wahl, R., Wendl, M. C. & Wyczalkowski, M. A., Mar 2022, In: Nature Methods. 19, 3, p. 262-267 6 p.

  Research output: Contribution to journal › Comment/debate

  Open Access
  16 Scopus citations

• Oligometastatic Rectal Adenocarcinoma Treated With Short-Course Radiation Therapy and Chemotherapy With Nonoperative Intent of the Primary for Locoregional Complete Responders

  Schiff, J. P., Chin, R. I., Roy, A., Mahapatra, L., Stowe, H. B., Andruska, N., Huang, Y., Mutch, M., Fields, R. C., Hawkins, W. G., Doyle, M., Chapman, W., Tan, B., Henke, L. E., Badiyan, S. N., DeSelm, C., Samson, P. P., Pedersen, K. & Kim, H., Sep 1 2022, In: Practical Radiation Oncology. 12, 5, p. e406-e414

  Research output: Contribution to journal › Article › peer-review

  • Adenocarcinoma 100%
  • Radiotherapy 88%
  • Drug Therapy 75%
  • Rectal Neoplasms 35%
  • Progression-Free Survival 21%
  1 Scopus citations

• Oncogenic Kras-Mediated Cytokine CCL15 Regulates Pancreatic Cancer Cell Migration and Invasion through ROS

  Messex, J. K., Adams, K. L. A., Hawkins, W. G., Denardo, D., Bardeesy, N., Billadeau, D. D. & Liou, G. Y., May 1 2022, In: Cancers. 14, 9, 2153.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Pancreatic Neoplasms 100%
  • Cell Movement 86%
  • Reactive Oxygen Species 84%
  • Adenocarcinoma 72%
  • Cytokines 65%
  5 Scopus citations

• Qualitative imaging features of pancreatic neuroendocrine neoplasms predict histopathologic characteristics including tumor grade and patient outcome

  Yano, M., Shetty, A., Williams, G. A., Lancia, S., Trikalinos, N. A., Hammill, C. W., Hawkins, W. G., Salter, A. & Chatterjee, D., Dec 2022, In: Abdominal Radiology. 47, 12, p. 3971-3985 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Pancreatic Neoplasms 100%
  • Blood Vessels 62%
  • Neoplasms 34%
  • Fibrosis 31%
  • Survival 23%
  2 Scopus citations

• Spatially restricted drivers and transitional cell populations cooperate with the microenvironment in untreated and chemo-resistant pancreatic cancer

  Cui Zhou, D., Jayasinghe, R. G., Chen, S., Herndon, J. M., Iglesia, M. D., Navale, P., Wendl, M. C., Caravan, W., Sato, K., Storrs, E., Mo, C. K., Liu, J., Southard-Smith, A. N., Wu, Y., Naser Al Deen, N., Baer, J. M., Fulton, R. S., Wyczalkowski, M. A., Liu, R., Fronick, C. C., & 46 othersFulton, L. A., Shinkle, A., Thammavong, L., Zhu, H., Sun, H., Wang, L. B., Li, Y., Zuo, C., McMichael, J. F., Davies, S. R., Appelbaum, E. L., Robbins, K. J., Chasnoff, S. E., Yang, X., Reeb, A. N., Oh, C., Serasanambati, M., Lal, P., Varghese, R., Mashl, J. R., Ponce, J., Terekhanova, N. V., Yao, L., Wang, F., Chen, L., Schnaubelt, M., Lu, R. J. H., Schwarz, J. K., Puram, S. V., Kim, A. H., Song, S. K., Shoghi, K. I., Lau, K. S., Ju, T., Chen, K., Chatterjee, D., Hawkins, W. G., Zhang, H., Achilefu, S., Chheda, M. G., Oh, S. T., Gillanders, W. E., Chen, F., DeNardo, D. G., Fields, R. C. & Ding, L., Sep 2022, In: Nature Genetics. 54, 9, p. 1390-1405 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Pancreatic Neoplasms 100%
  • Population 41%
  • Neoplasms 34%
  • Proteogenomics 29%
  • Adenocarcinoma 27%
  35 Scopus citations

• The targeted SMAC mimetic SW IV-134 augments platinum-based chemotherapy in pre-clinical models of ovarian cancer

  Binder, P. S., Hashim, Y. M., Cripe, J., Buchanan, T., Zamorano, A., Vangveravong, S., Mutch, D. G., Hawkins, W. G., Powell, M. A. & Spitzer, D., Dec 2022, In: BMC Cancer. 22, 1, 263.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • SW IV-134 100%
  • Platinum 43%
  • Caspases 42%
  • Ovarian Neoplasms 37%
  • Mitochondria 34%
  2 Scopus citations
• 2023

  4,300 steps per day prior to surgery are associated with improved outcomes after pancreatectomy

  Cos, H., Zárate Rodríguez, J. G., Srivastava, R., Bewley, A., Raper, L., Li, D., Dai, R., Williams, G. A., Fields, R. C., Hawkins, W. G., Lu, C., Sanford, D. E. & Hammill, C. W., Jan 2023, In: HPB. 25, 1, p. 91-99 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Pancreatectomy 100%
  • Exercise 27%
  • Regression Analysis 13%
  • Logistic Models 13%
  • Physical Fitness 12%

• Area deprivation and rurality impact overall survival and adjuvant therapy administration in patients with pancreatic ductal adenocarcinoma (PDAC)

  Pothuri, V., Zárate Rodriguez, J. G., Kasting, C., Leigh, N., Hawkins, W. G., Sanford, D. E. & Fields, R., 2023, (Accepted/In press) In: HPB.

  Research output: Contribution to journal › Article › peer-review

  • Adenocarcinoma 100%
  • Survival 70%
  • Vulnerable Populations 49%
  • Therapeutics 20%
  • Proportional Hazards Models 14%

• Comments on “Challenging Orthodoxy_ Beyond the Critical View of Safety”

  Strasberg, S. M., Brunt, L. M., Fields, R. C., Alseidi, A. & Hawkins, W. G., Jun 2023, In: Journal of Gastrointestinal Surgery. 27, 6, p. 1292-1293 2 p.

  Research output: Contribution to journal › Letter › peer-review

• Correction to: Comments on “Challenging Orthodoxy_ Beyond the Critical View of Safety” (Journal of Gastrointestinal Surgery, (2023), 27, 6, (1292-1293), 10.1007/s11605-023-05685-x)

  Strasberg, S. M., Brunt, L. M., Fields, R. C., Alseidi, A. & Hawkins, W. G., Jun 2023, In: Journal of Gastrointestinal Surgery. 27, 6, p. 1295 1 p.

  Research output: Contribution to journal › Comment/debate

  Open Access

  • Safety 100%

• How Biomarkers of Response to Chemotherapy Might Change Patient Management

  Hawkins, W. G., Hammill, C. W. & Ballentine, S. J., Feb 2023, In: Annals of Surgical Oncology. 30, 2, p. 658-659 2 p.

  Research output: Contribution to journal › Comment/debate

  Open Access

• Induction of cancer neoantigens facilitates development of clinically relevant models for the study of pancreatic cancer immunobiology

  Panni, U. Y., Chen, M. Y., Zhang, F., Cullinan, D. R., Li, L., James, C. A., Zhang, X., Rogers, S., Alarcon, A., Baer, J. M., Zhang, D., Gao, F., Miller, C. A., Gong, Q., Lim, K. H., DeNardo, D. G., Goedegebuure, S. P., Gillanders, W. E. & Hawkins, W. G., Aug 2023, In: Cancer Immunology, Immunotherapy. 72, 8, p. 2813-2827 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Pancreatic Neoplasms 100%
  • Clone Cells 71%
  • Adenocarcinoma 70%
  • T-Lymphocytes 46%
  • Cell Line 44%

• MR-Guided Radiation Therapy With Concurrent Gemcitabine/Nab-Paclitaxel Chemotherapy in Inoperable Pancreatic Cancer: A TITE-CRM Phase I Trial

  Kim, H., Olsen, J. R., Green, O. L., Chin, R. I., Hawkins, W. G., Fields, R. C., Hammill, C., Doyle, M. B., Chapman, W., Suresh, R., Tan, B., Pedersen, K., Jansen, B., DeWees, T. A., Lu, E., Henke, L. E., Badiyan, S., Parikh, P. J., Roach, M. C., Wang-Gillam, A., & 1 othersLim, K. H., Jan 1 2023, In: International Journal of Radiation Oncology Biology Physics. 115, 1, p. 214-223 10 p.

  Research output: Contribution to journal › Article › peer-review

  • 130-nm albumin-bound paclitaxel 100%
  • chemotherapy 93%
  • gemcitabine 72%
  • radiation therapy 64%
  • Pancreatic Neoplasms 61%
  3 Scopus citations

• Postoperative Proton Pump Inhibitors are associated with a significantly higher rate of delayed gastric emptying after pancreatoduodenectomy

  Panni, U., Srivastava, R., Bewley, A., Williams, G. A., Fields, R. C., Sanford, D. E., Hawkins, W. G., Leigh, N. & Hammill, C. W., Jun 2023, In: HPB. 25, 6, p. 659-666 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Pancreaticoduodenectomy 100%
  • Gastric Emptying 96%
  • Proton Pump Inhibitors 95%
  • Peptic Ulcer 25%
  • Pancreatic Fistula 15%

• Stromal and therapy-induced macrophage proliferation promotes PDAC progression and susceptibility to innate immunotherapy

  Zuo, C., Baer, J. M., Knolhoff, B. L., Belle, J. I., Liu, X., de la Lastra, A. A., Fu, C., Hogg, G. D., Kingston, N. L., Breden, M. A., Dodhiawala, P. B., Zhou, D. C., Lander, V. E., James, C. A., Ding, L., Lim, K. H., Fields, R. C., Hawkins, W. G., Weber, J. D., Zhao, G., & 1 othersDenardo, D. G., Jun 5 2023, In: Journal of Experimental Medicine. 220, 6, e20212062.

  Research output: Contribution to journal › Article › peer-review

  • Immunotherapy 100%
  • Adenocarcinoma 89%
  • Macrophages 79%
  • Neoplasms 33%
  • Macrophage Colony-Stimulating Factor 25%
  3 Scopus citations